Publications by authors named "William Auteri"

Purpose: The management of tandem extracranial internal carotid artery and intracranial large vessel occlusion during endovascular thrombectomy (EVT) for acute ischemic stroke (AIS) has been under-investigated. We sought to investigate outcomes of AIS patients with tandem occlusion (TO) treated with carotid artery stenting (CAS) compared to those not treated with CAS (no-CAS) during EVT.

Methods: We performed a cohort study using data from AIS patients enrolled in the Italian Registry of Endovascular Treatment in Acute Stroke.

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Background: There are limited data concerning procedure-related complications of endovascular thrombectomy for large vessel occlusion strokes.

Aims: We evaluated the cumulative incidence, the clinical relevance in terms of increased disability and mortality, and risk factors for complications.

Methods: From January 2011 to December 2017, 4799 patients were enrolled by 36 centers in the Italian Registry of Endovascular Stroke Treatment.

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Background And Purpose: To evaluate outcome and safety of endovascular treatment beyond 6 hours of onset of ischemic stroke due to large vessel occlusion in the anterior circulation, in routine clinical practice.

Methods: From the Italian Registry of Endovascular Thrombectomy, we extracted clinical and outcome data of patients treated for stroke of known onset beyond 6 hours. Additional inclusion criteria were prestroke modified Rankin Scale score ≤2 and ASPECTS score ≥6.

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Article Synopsis
  • There is currently no reliable system to predict the risk of symptomatic intracerebral hemorrhage after thrombectomy for ischemic stroke, prompting the development of a nomogram to address this issue.
  • The study analyzed data from 3714 patients treated for large vessel occlusion and created the IER-SICH nomogram based on various factors, including age and procedure time, to assess hemorrhage risk.
  • The IER-SICH nomogram demonstrated good predictive ability, with area under the curve values of 0.778 in the training set and 0.709 in the test set, making it the first validated model for early identification of high-risk patients post-thrombectomy.
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Article Synopsis
  • The study aimed to create and validate a new nomogram, called IER-START, to predict unfavorable outcomes in stroke patients with large vessel occlusion who received intervention within 6 hours.
  • This nomogram was based on key factors like the NIH Stroke Scale score, age, previous disability levels, and treatment methods, utilizing data from the Italian Endovascular Registry.
  • The IER-START model demonstrated strong predictive performance, with an AUC-ROC of 0.838 in training and 0.820 in testing, making it a reliable tool for assessing patient outcomes after thrombectomy.
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Purpose: To prospectively assess if middle cerebellar peduncle (MCP) atrophy, evaluated at magnetic resonance (MR) imaging, can help differentiate multiple system atrophy (MSA) from Parkinson disease (PD).

Materials And Methods: All participants provided informed consent for participation in the study, which was approved by the institutional review board. Sixteen consecutive patients with MSA, 26 consecutive patients with PD, and 14 healthy control subjects were examined with MR imaging.

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Cerebral venous outflow abnormalities, as transverse sinuses (TSs) stenosis,may underlie a picture of idiopathic intracranial hypertension (IIH). To identify the best non-invasive MR venography (MRV) technique for exploring the disturbance of flow of TSs in IIH patients, we compared three dimensional phase contrast (3-DPC) MRV images, acquired with different velocity encodings (15 and 40 cm/s) with two-dimensional time-of-flight (2D-TOF) MR images in 6 subjects with IIH and 12 age-matched normal controls. In both groups, we also measured flow velocity in TSs by using single slice 2D-CINE PC acquisitions.

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