Publications by authors named "William Armando Alvarez"
Softepigen: Primers Design Web-Based Tool for MS-HRM Technique.
IEEE/ACM Trans Comput Biol Bioinform
January 2021
Article Synopsis
- MS-HRM (Methylation Sensitive High-Resolution Melting) is a technique used for assessing DNA methylation, which requires specific primer design recommendations for effective results.
- There was previously no automated software to help design these primers, but the introduction of Softepigen changes that by allowing users to focus on complex genomic regions for better specificity.
- Softepigen has been validated through in-silico PCR analysis, demonstrating satisfactory specificity, and is now available for free use on their website, www.soft-epigen.com.