Publications by authors named "William A Takang"

Background: Stillbirth is a common adverse pregnancy outcome worldwide, with an estimated 2.6 million stillbirths yearly. In Cameroon, the reported rate in 2015 was 19.

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Key Clinical Message: Twin pregnancies in homozygous sickle cell patients are not only uncommon in our setting but are most often associated with adverse maternal-fetal outcomes especially in primary healthcare facilities where most of these cases initially present due to financial constraints, though lacking the necessary technical platform (including blood banks) to properly manage them.

Abstract: We are reporting the case of the preterm management of sickle cell crises in a twin pregnancy with poor antenatal care uptake in a primary healthcare facility devoid of a blood bank in Cameroon. Ngungi Fely, a 21-year-old HbSS patient, of the Bakweri tribe G3P0020, blood group O rhesus positive, was admitted at our health facility at 33 3/7 weeks' gestation with twin pregnancy, clinical anemia (hemoglobin 3.

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Background: Malaria remains a burden for pregnant women and the under 5. Intermittent preventive treatment of pregnant women (IPTp) for malaria with sulfadoxine - pyrimethamine (SP) has since replaced prophylaxis and legislation has been reinforced in the area of insecticide treated mosquito nets (ITNs) in Cameroon. Clinical malaria despite all these measures remains a problem.

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Article Synopsis
  • Recent studies show that superinfection with different HIV-1 subtypes can boost the immune response, specifically the generation of neutralizing antibodies (nAbs) against diverse HIV-1 strains.
  • However, research comparing superinfected individuals to those with single subtype infections found no significant difference in their ability to neutralize early autologous (same strain) viruses.
  • Ultimately, while superinfection helps the immune system respond to a wider array of HIV-1 variants, it does not enhance the potency against the individual's own strain compared to purely singly infected patients.
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