A new use for old drugs: identifying compounds with an anti-obesity effect using a high through-put semi-automated screening platform.

Obesity is one of the most common global health problems for all age groups with obese people at risk of a variety of associated health complications. Consequently, there is a need to develop new therapies that lower body fat without the side effects. However, obesity is a complex and systemic disease, so that results are not easily translatable to clinical situations.

LC-MS/MS assay for the quantification of testosterone, dihydrotestosterone, androstenedione, cortisol and prednisone in plasma from castrated prostate cancer patients treated with abiraterone acetate or enzalutamide.

Prostate cancer is the most common malignancy among men in the Western world. Treatment of this patient population, e.g.