Publications by authors named "Willemijn Josepha Jansen"
Alzheimers Dement
November 2023
Article Synopsis
- This study explored the relationship between locus coeruleus (LC) degeneration and small blood vessel disease in the brain using data from two large neuropathology studies.
- Researchers found that LC hypopigmentation was linked to higher odds of cerebral amyloid angiopathy (CAA) and arteriolosclerosis, indicating a connection between LC pathology and vascular issues, independent of Alzheimer's disease pathology.
- The findings suggest that degeneration of the LC may influence the pathways connecting vascular health to Alzheimer's disease, highlighting the need for further research on the LC-norepinephrine system in relation to brain health.
