Publications by authors named "Willem-Jan van der Woude"

Article Synopsis
  • The study assessed the placement of the Slim Modiolar Electrode (SME) using the extended Round Window (eRW) method, focusing on its impact on hearing preservation and speech perception.
  • Twenty-three adults were implanted with the SME; their electrode positioning was monitored both during and after surgery, with evaluations on hearing and speech conducted 2 and 12 months later.
  • The results showed effective electrode insertion and significant improvement in speech perception, but only moderate residual hearing preservation, suggesting the eRW method may not be universally applicable for all patients.
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Article Synopsis
  • Cochlear implantation can lead to inflammation, fibrosis, and new bone formation (NBF), potentially affecting residual hearing.
  • A study involving 123 participants analyzed NBF using ultra-high-spatial-resolution CT and found it present in 68% of cases, primarily around the basal electrode contacts.
  • Significant associations were observed between NBF and both electrode type and surgical technique, indicating that different approaches may influence hearing outcomes post-implantation.
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Objectives: The primary objective of this study is to identify the biographic, audiologic, and electrode position factors that influence speech perception performance in adult cochlear implant (CI) recipients implanted with a device from a single manufacturer. The secondary objective is to investigate the independent association of the type of electrode (precurved or straight) with speech perception.

Design: In a cross-sectional study design, speech perception measures and ultrahigh-resolution computed tomography scans were performed in 129 experienced CI recipients with a postlingual onset of hearing loss.

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Background And Objective: Performing patient-specific, pre-operative cochlea CT-based measurements could be helpful to positively affect the outcome of cochlear surgery in terms of intracochlear trauma and loss of residual hearing. Therefore, we propose a method to automatically segment and measure the human cochlea in clinical ultra-high-resolution (UHR) CT images, and investigate differences in cochlea size for personalized implant planning.

Methods: 123 temporal bone CT scans were acquired with two UHR-CT scanners, and used to develop and validate a deep learning-based system for automated cochlea segmentation and measurement.

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In subtraction CT angiography (CTA), a non-contrast CT acquisition is subtracted from a contrast-enhanced CTA acquisition. Subtraction CTA can be applied in the detection, classification, and follow-up of intracranial aneurysms and is advantageous over conventional angiography because of its non-invasive nature, shorter examination time, and lower costs. Recently, an ultra-high-resolution CT scanner has been introduced in clinical practice offering an in-plane spatial resolution of up to 0.

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Objectives: We present a novel One-Step-Stroke protocol for wide-detector CT scanners that interleaves cerebral CTP with volumetric neck CTA (vCTA). We evaluate whether the resulting time gap in CTP affects the accuracy of CTP values.

Methods: Cerebral CTP maps were retrospectively obtained from 20 patients with suspicion of acute ischemic stroke and served as the reference standard.

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Objectives: Feasibility evaluation of the One-Step Stroke Protocol, which is an interleaved cerebral computed tomography perfusion (CTP) and neck volumetric computed tomography angiography (vCTA) scanning technique using wide-detector computed tomography, and to assess the image quality of vCTA.

Methods: Twenty patients with suspicion of acute ischaemic stroke were prospectively scanned and evaluated with a head and neck CTA and with the One-Step Stroke Protocol. Arterial enhancement and contrast-to-noise ratio (CNR) in the carotid arteries was assessed.

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Purpose: Optimizing CT brain perfusion protocols is a challenge because of the complex interaction between image acquisition, calculation of perfusion data, and patient hemodynamics. Several digital phantoms have been developed to avoid unnecessary patient exposure or suboptimum choice of parameters. The authors expand this idea by using realistic noise patterns and measured tissue attenuation curves representing patient-specific hemodynamics.

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