Differentiation between normal and metastatic lymph nodes in patients with skin melanoma: Preliminary findings using a DIXON-based whole-body MRI approach.

Purpose: Metastatic melanoma lymph nodes (MMLns) might be challenging to detect on MR-WBI, as both MMLns and normal lymph nodes (NLns) can show restricted water diffusion. Our purpose is to assess the potential contribution of the DIXON sequence in differentiating MMLns from NLns.

Material And Methods: We followed a cohort of 107 patients with stage IIIb/c and IV skin melanoma for 32 months using MR-WBI with DIXON, STIR, and DWI/ADC sequences.

Physical activity increases synovial fluid in ankle tendon sheaths: an adjustment of MR Criteria is needed.

Objectives: To compare the amount of fluid in synovial sheaths of the ankle before and after running. Our hypothesis was that this amount would increase and that the threshold for what is normally acceptable should be adjusted after physical activity.

Methods: Twenty-one healthy volunteers (n = 42 ankles) ran for 40 min on a treadmill.

Pseudo-tendinopathy on MRI of the navicular and tarsometatarsal parts of the tibialis posterior tendon: A study in normal individuals.

Purpose: To determine the normal thickness and MRI appearance of the Tibialis Posterior Tendon near the navicular insertion in normal volunteers.

Materials And Methods: By using a 3T MRI system 41 ankles were imaged, and PD weighted images with fat saturation were acquired in the three orthogonal planes. Symptoms of tendon pathology and history of trauma or surgery of the tendon were used as volunteer exclusion criteria.

Improved automated early detection of breast cancer based on high resolution 3D micro-CT microcalcification images.

Background: The detection of suspicious microcalcifications on mammography represents one of the earliest signs of a malignant breast tumor. Assessing microcalcifications' characteristics based on their appearance on 2D breast imaging modalities is in many cases challenging for radiologists. The aims of this study were to: (a) analyse the association of shape and texture properties of breast microcalcifications (extracted by scanning breast tissue with a high resolution 3D scanner) with malignancy, (b) evaluate microcalcifications' potential to diagnose benign/malignant patients.

Repeatability and reproducibility of ADC measurements: a prospective multicenter whole-body-MRI study.

Objectives: Multicenter oncology trials increasingly include MRI examinations with apparent diffusion coefficient (ADC) quantification for lesion characterization and follow-up. However, the repeatability and reproducibility (R&R) limits above which a true change in ADC can be considered relevant are poorly defined. This study assessed these limits in a standardized whole-body (WB)-MRI protocol.

Pseudo-tear appearance of the Achilles tendon on MR imaging in normal volunteers.

Purpose: The aim of this study was to confirm our clinical observation that a pseudo-tear appearance of the Achilles tendon is commonly seen on MRI and is of no clinical relevance.

Materials And Methods: Forty-one ankles were imaged on a 3 T MR system, and PD weighted images with fat saturation were obtained in three orthogonal planes (TR, 2969 ms; TE, 30 ms; NA, 2; slice thickness, 2.5 mm).

Fluid distribution in ankle tendon sheaths in healthy volunteers: MRI findings.

Purpose: To assess normal distribution of fluid in the tendon sheaths of the ankle.

Methods: 21 healthy volunteers were evaluated. Bilateral ankle MRI was performed on a 3T unit with PD-weighted images with fat saturation.

Pseudo-tear appearance of the posterior tibiotalar ligament on fluid-sensitive sequences.

Purpose: This study aimed at studying the MR imaging appearance of the tibiotalar ligament in asymptomatic volunteers.

Materials And Methods: Fourty-two ankles were imaged on a 3T MR system using proton density weighted images with fat saturation (TR, 2969 ms; TE 30 ms; NA, 2; slice thickness, 2.5 mm).

Improved enhancement in CT angiography with reduced contrast media iodine concentrations at constant iodine dose.

The study objective is to investigate the impact of a wide range of contrast media (CM) iodine concentrations on CT enhancement at constant total iodine dose (TID) and iodine delivery rate (IDR). Seven injection protocols, based on different iodine concentrations ranging from 120 to 370 mg I/mL, were assessed on 4 minipigs at a constant TID of 320 mg I/kg and IDR of 0.64 g I/s.

Bone scan findings in erythromelalgia.

The use of hyaluronic acid nanoshells has been proposed to encapsulate prodrugs and exploit the mechanisms of interactions between living cells, like endocytes or cancer cells and hyaluronic acid, which is a natural component of the extracellular matrix. In this review we describe the potential and the limits of this promising research trend and discuss the theoretical advantages of such an engineering approach. Is it a possible scalability to increase the efficacy and biodegradability of molecules like contrast media and radiotracers especially for neuroradiology and nuclear medicine studies.

Radiography of the distal extremity of the manus in the donkey foal: Normal images and quantitative characterization from birth to 2 years of age: A pilot study.

This study describes a radiographic survey of the anatomical development of the distal extremity of the manus in the donkey from 0 to 2 years of age. The right distal limb of 10 donkey foals, born in the spring of 2012, underwent radiographs every month for the first 6 months of age and every 3 months during the following 18 months. Latero-medial radiographs with and without barium marker at the coronary band and dorso-palmar radiographs with both front feet in weight bearing were obtained.

Fluid distribution in ankle and midfoot joints: MR findings in asymptomatic volunteers.

Purpose: The purpose of this study is to assess the amount of fluid in the joints of the ankle and midfoot on MR imaging in asymptomatic volunteers.

Materials And Methods: Twenty-one healthy asymptomatic volunteers (42 ankles) were evaluated with MRI imaging. There were 13 men and 8 women.

The Impact of Combining a Low-Tube Voltage Acquisition with Iterative Reconstruction on Total Iodine Dose in Coronary CT Angiography.

Objectives: To assess the impact of combining low-tube voltage acquisition with iterative reconstruction (IR) techniques on the iodine dose in coronary CTA.

Methods: Three minipigs underwent CCTA to compare a standard of care protocol with two alternative study protocols combining low-tube voltage and low iodine dose with IR. Image quality was evaluated objectively by the CT value, signal-to-noise ratio (SNR), and contrast-to-noise ratio (CNR) in the main coronary arteries and aorta and subjectively by expert reading.

Liver Abscess Due to Dropped Appendicolith after Laparoscopic Appendectomy.

The lifetime risk of appendicitis is 6 to 7 % [1]. When appendicitis is clinically suspected, an appendicolith can be found in 30% of the patients [2]. An appendicolith may be retained post-operatively ('dropped appendicolith') due to previous perforation, non-recognition during surgery or the impossibility to remove it.

Correlative bone imaging in a case of Schnitzler's syndrome and brief review of the literature.

Unlabelled: Schnitzler's syndrome is a rare disease characterized by a monoclonal IgM (or IgG) paraprotein, a nonpruritic urticarial skin rash, and 2 (or 3) of the following: recurrent fever, objective signs of abnormal bone remodeling, elevated CRP level or leukocytosis, and a neutrophilic infiltrate on skin biopsy. It responds well to treatment with the interleukine-1-inhibitor anakinra. We report the bone scintigraphy and MRI findings in a 45 years old man with this syndrome and compare them with data from the literature.

Rapid malignant transformation of primary synovial chondromatosis into chondrosarcoma.

Chondrosarcoma of the synovium is rare. It may arise de novo from the synovium or pre-existing synovial chondro- matosis may undergo malignant transformation into chondrosarcoma. Diagnosing a malignant transformation of the synovium remains a big challenge.

Correlative imaging in gallbladder carcinoma.

Gallbladder carcinoma is a relatively rare malignant epithelial neoplasm, arising from gallbladder mucosa. It is the fifth most common gastrointestinal malignancy and the most common biliary tract cancer. Early diagnosis remains difficult, because clinical symptoms are sparse and non-specific, often resulting in advanced stage disease at the time of diagnosis.

Ultrasound follow-up of posttraumatic injuries of the sagittal band of the dorsal hood treated by a conservative approach.

Traumatic dislocation of the extensor tendon over the metacarpophalangeal (MCP) joint is a rare problem in patients without rheumatoid disorders. The common extensor tendon is stabilized on the metacarpal head by components of the dorsal hood (DH). A tear in the sagittal bands, allows (sub)luxation of the tendon.

Segond fracture: involvement of the iliotibial band, anterolateral ligament, and anterior arm of the biceps femoris in knee trauma.

Objective: To evaluate the involvement of the iliotibial band (ITB), the anterolateral ligament (ALL), and the anterior arm of the biceps femoris in MRI-diagnosed Segond fracture and to evaluate other associated findings of Segond fracture.

Materials And Methods: We retrospectively reviewed the MRI of 13 cases of Segond fracture. The studies included proton density-weighted, T2-weighted, and proton density-weighted with fat saturation images in the three planes.