Publications by authors named "Will Herrington"

Article Synopsis
  • The KDIGO Clinical Practice Guideline for Chronic Kidney Disease (CKD) updates the 2012 guideline, reflecting a comprehensive review of new evidence and advancements in treatment but does not apply to dialysis patients or those with transplants.
  • The guideline addresses evaluation, risk assessment, and management strategies to slow CKD progression, using a systematic approach to assess the quality and strength of recommendations.
  • It includes practice points, infographics, and highlights future research needs, aiming to serve a wide audience and consider implications for healthcare policies and payment systems.*
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Background: The use of mobile devices in clinical research has advanced substantially in recent years due to the rapid pace of technology development. With an overall aim of informing the future use of mobile devices in interventional clinical research to measure primary outcomes, we conducted a systematic review of the use of and clinical outcomes measured by mobile devices (mobile outcomes) in observational and interventional clinical research.

Method: We conducted a PubMed search using a range of search terms to retrieve peer-reviewed articles on clinical research published between January 2010 and May 2016 in which mobile devices were used to measure study outcomes.

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Background: Kidney transplantation is the best treatment for patients with end-stage renal failure, but uncertainty remains about the best immunosuppression strategy. Long-term graft survival has not improved substantially, and one possible explanation is calcineurin inhibitor (CNI) nephrotoxicity. CNI exposure could be minimized by using more potent induction therapy or alternative maintenance therapy to remove CNIs completely.

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