Publications by authors named "Will Cordell"
Open Forum Infect Dis
January 2024
Article Synopsis
- Consensus guidelines suggest collecting two serum concentrations of vancomycin to estimate its effectiveness, but using Bayesian software allows for monitoring with just one concentration, although this method lacks extensive validation.
- A retrospective study involving 300 adult patients with gram-positive infections found that those receiving AUC-guided therapy had better treatment outcomes, including higher success rates and lower instances of acute kidney injury (VA-AKI) compared to those on trough-guided therapy.
- Results indicate that AUC-guided therapy not only improved patient safety by reducing VA-AKI but also allowed for more efficient and flexible monitoring, ultimately leading to better overall outcomes without loss of treatment efficacy.
