Digital vs manual axis marking for toric phakic intraocular lens alignment: prospective randomized intraindividual trial.

Purpose: To compare visual and refractive outcomes and postoperative axis alignment for toric implantable collamer lens (ICL) implantation in astigmatic myopia using manual vs digital marking techniques.

Setting: Department of Ophthalmology, Medical University of Graz, Graz, Austria.

Design: Prospective randomized single-centered intraindividual comparison.

Changes of individual retinal layer thickness post-uneventful cataract surgery determined by spectral-domain optical coherence tomography over a 3-months period.

Purpose: To evaluate retinal thickness changes of individual retinal layers using spectral-domain optical coherence tomography (SD-OCT) after uneventful cataract surgery over a 3-months period.

Design: Prospective cohort study.

Methods: 41 patients who underwent uneventful cataract surgery were included.

Paracentral acute middle maculopathy in otherwise, young healthy female patients.

Purpose: The retina is supplied with blood through superficial and deep capillary systems. Paracentral acute middle maculopathy (PAMM) is a relatively new terminology based on pathognomonic findings in the spectral-domain optical coherence tomography (SD-OCT). A connection with various retinal vascular diseases has been described, which is indicative of an ischemic etiology.

The impact of surgeon's experience and sex on the incidence of cystoid macular edema after uneventful cataract surgery.

Purpose: To assess the rate of pseudophakic cystoid macular edema (pCME) in uneventful cataract surgery in surgeons in training vs experienced surgeons and to analyze the rate of pCME according to surgeon's sex.

Methods: Medical reports post phacoemulsification between 2010 and 2018 at the Department of Ophthalmology, Medical University of Graz, Austria, were reviewed for pCME. A running lifetime number of preceding cataract surgeries was used to express hands-on experience.

Blindness and visual impairment in Central Europe.

Purpose: To assess the prevalence and causes of visual impairment and blindness in a Central European country. The findings may have implications for the planning of further research and development of therapies in order to prevent blindness.

Setting: Department of Ophthalmology, Medical University of Graz, Austria.

Evaluation of Acanthamoeba keratitis cases in a tertiary medical care centre over 21 years.

To report on Acanthamoeba keratitis cases in a tertiary university eye-hospital in Graz, Austria, over a 21-year period. Retrospective study. Parameters included demographics, diagnostics, clinical courses, medical therapies, surgical interventions, secondary complications, and best spectacle-corrected visual acuity (BSCVA).

Gender differences in albumin and ascorbic acid in the vitreous antioxidant system.

Ascorbic acid is present at high concentrations in the vitreous and plays a central role in vitreous redox chemistry. Albumin is the main protein in the vitreous with antioxidant properties and occurs in different oxidation states, which can be used as redox indicators, but have not been studied in the vitreous. This study, therefore, addressed the vitreous redox state of cysteine-34 of albumin in relation to the ascorbic acid content, which has been suggested to exert a main function in detoxifying reactive oxygen in the vitreous.

Vitreous hyper-reflective dots in pseudophakic cystoid macular edema assessed with optical coherence tomography.

Purpose: This study compares the presence of vitreous hyper-reflective dots (VHDs) detected with optical coherence tomography (OCT) between eyes with pseudophakic cystoid macular edema (CME) and those with no CME after cataract surgery. In addition, we evaluated the impact of VHDs on the responsiveness of pseudophakic CME to cortisone treatment.

Setting: Department of Ophthalmology, Medical University of Graz, Austria.

Depth of focus after implantation of spherical or aspheric intraocular lenses in hyperopic and emmetropic patients.

Purpose: To evaluate whether hyperopic patients with short axial length and high dioptric intraocular lens (IOL) power can achieve a higher depth of focus after implantation of a monofocal spherical or aspheric IOL than emmetropic patients.

Setting: Department of Ophthalmology, Medical University Graz, Graz, Austria.

Design: Prospective case series.

Prevalence of posterior vitreous detachment in glaucoma patients and controls.

Purpose: To evaluate the impact of oxidative stress - present in glaucoma - on the vitreous. We therefore compare the presence of early and late stages of posterior vitreous detachment (PVD) between patients with glaucoma and controls.

Methods: The vitreous state was evaluated by the combination of optical coherence tomography and ultrasound.

Analysis of functional polymorphisms in apoptosis-related genes in primary open angle glaucoma.

Purpose: Glaucoma is a disease with high heritability in which the degradation of retinal ganglion cells occurs via apoptosis. Therefore, we investigated the role of four functional apoptosis-related gene variants (Akt1 rs1130233, Bax rs4645878, Fas rs223476, and FasL rs763110) in patients with primary open angle glaucoma.

Methods: 334 patients with primary open angle glaucoma and 334 controls were recruited for this case-control study.