Acute respiratory failure secondary to primary spontaneous pneumothorax.

Primary spontaneous pneumothorax occasionally occurs in young healthy individuals. Most of the time, it is diagnosed before it progresses to acute respiratory failure. We present a healthy young girl who developed acute respiratory failure secondary to primary spontaneous pneumothorax.

In vitro activity and synergy of bismuth thiols and tobramycin against Burkholderia cepacia complex.

Objectives: To determine the susceptibility of Burkholderia multivorans and Burkholderia cenocepacia to bismuth-thiols (BTs), and to examine the synergistic effects of tobramycin and subinhibitory concentrations of BTs against these organisms.

Methods: The susceptibilities of 25 clinical isolates each of B. multivorans and B.