Publications by authors named "Wijak Kongwattananon"
Objective: To characterize changes in the retinal microvasculature in eyes with birdshot chorioretinopathy (BCR) using OCT angiography (OCTA).
Design: Retrospective, observational, single center.
Subjects: Twenty-eight patients (53 eyes) with BCR and 59 age-matched controls (110 eyes).
Extralymphatic filariasis caused by filaria of zoonotic origins has been frequently reported in Thailand over recent years. Here, we report the first case of ocular filariasis in a 7.5-year-old Thai boy who initially presented with progressive conjunctival redness and blurred vision in his right eye.
View Article and Find Full Text PDFPurpose Of Review: This article reviewed and summarized recent published data on ocular imaging findings and treatment of posterior segment manifestations of ocular metastasis.
Recent Findings: Advanced ocular imaging can help differentiate ocular metastases from other mimicking lesions, including primary intraocular tumors or infections. Recently, case reports have demonstrated the successful use of targeted systemic therapy to achieve local control of vitreous and choroidal metastases.
Optical Coherence Tomography Angiography Biomarkers in Thai Patients With Diabetic Nephropathy: A Diabetic Eye and Kidney Diseases (DEK-D) Study.
Transl Vis Sci Technol
April 2023
Purpose: To identify optical coherence tomography angiography (OCTA) biomarkers to predict the diabetic nephropathy (DN) and their associations with 24-hour urine albumin levels in diabetic patients.
Methods: This cross-sectional, observational study examined 186 eyes from 93 individuals subdivided into three groups according to 24-hour urine albumin levels: no DN, early DN, and late DN. Vessel density (VD), fractal dimension, foveal avascular zone area, intercapillary area, central retinal thickness, and subfoveal choroidal thickness were measured from OCTA images to determine their association with the DN stages.
Granulomatous panuveitis in disseminated sporotrichosis: case report and review of the literature.
J Ophthalmic Inflamm Infect
March 2023
Purpose: To report a case of intraocular sporotrichosis presenting with bilateral granulomatous panuveitis.
Methods: Observational case report and literature review.
Case Presentation: A 62-year-old woman with a history of polycythemia vera presented with a non-healing ulcer at the left index finger, generalized erythematous papules, and bilateral granulomatous panuveitis.
Article Synopsis
- Tumor necrosis factor inhibitors (TNFis) can cause the body to create antidrug antibodies (ADAs), which may lead to a decrease in treatment effectiveness for patients with noninfectious uveitis (NIU).
- The study aimed to investigate the frequency of ADAs and their relationship with drug levels and clinical outcomes in NIU patients receiving adalimumab or infliximab at the National Eye Institute from 2017 to 2021.
- Results showed that patients with detectable ADAs had significantly lower drug levels, indicating that ADA formation is linked to reduced effectiveness of TNFis in treating NIU.
Background: In Thailand, several novel laboratory investigations are recently available to help differentiate the uveitic etiologies. The update on uveitis epidemiological data in Thailand is necessary to better understand the disease burden and provide guidance on management. The current study aims to describe the prevalence and identify factors associated with poor visual outcomes of uveitis patients at a tertiary center in Thailand.
View Article and Find Full Text PDFPurpose: The purpose of this article is to report a case of ocular gnathostomiasis presenting with acute anterior uveitis and uveitis glaucoma.
Methods: observational case report and literature review.
Results: A 56-year-old Thai male was referred to a tertiary eye center with acute anterior uveitis and uveitis glaucoma in the right eye.
Purpose: To report a patient with vitreoretinal lymphoma (VRL) secondary to systemic diffuse large B-cell lymphoma, who had two episodes of spontaneous regression.
Observations: An 80-year-old Nicaraguan male with a history of treated systemic diffuse large B-cell lymphoma presented with decreased vision in his right eye over one year. The patient was found to have subretinal lesions and moderate vitreous opacities in his right eye.
Purpose: To investigate the utility of optical coherence tomography angiography (OCTA) for the detection of inflammatory choroidal neovascularization (iCNV) and monitoring their response to treatment.
Methods: A retrospective review of patients with a diagnosis of uveitis and associated iCNV with active exudation was performed. Active iCNV was determined by spectral domain OCT and/or fluorescein angiogram.
Changes in Choroidal Vascularity Index (CVI) in Intermediate Uveitis.
Transl Vis Sci Technol
December 2021
Purpose: To investigate the longitudinal changes in choroidal vascularity index (CVI) in eyes with active and quiescent intermediate uveitis using enhanced depth imaging optical coherence tomography (EDI-OCT).
Methods: EDI-OCT images of eyes with active and quiescent intermediate uveitis were retrospectively reviewed and binarized using ImageJ software. Choroidal parameters including CVI, total choroidal area (TCA), luminal area (LA), stromal area (SA), and subfoveal choroidal thickness (SCT) were measured and compared between baseline and follow-up visits among eyes with active and quiescent intermediate uveitis.
Purpose Of Review: There are an increasing number of publications related to dengue ophthalmic manifestations and multimodality imaging related to dengue. This review summarizes the current literature, describe ocular manifestations, current using of ocular imaging/investigations, and management of ocular dengue.
Recent Findings: Ocular manifestations of dengue can be present in many stages of dengue fever including after the resolution of systemic disease.
Article Synopsis
- The study aimed to assess changes in retinal blood vessels in patients with ocular Behcet's disease using advanced imaging techniques like OCTA and FA.
- A total of 21 patients were examined, revealing that the thickness of the fovea and the areas of poor blood flow in the retina correlated with visual acuity.
- The findings suggest that OCTA is a useful, non-invasive tool to identify early signs of macular ischemia in Behcet's disease, indicating that damage to the deep capillary plexus is more significant than that of the superficial plexus, leading to vision loss.