Publications by authors named "Wieslaw Hulak"
Polymorphisms in the GNAS Gene as Predictors of Ventricular Tachyarrhythmias and Sudden Cardiac Death: Results From the DISCOVERY Trial and Oregon Sudden Unexpected Death Study.
Heinrich Wieneke Jesper Hastrup Svendsen Jeffrey Lande Sebastian Spencker Juan Gabriel Martinez Wieslaw Hulak
J Am Heart Assoc
November 2016
Article Synopsis
- The study investigated the genetic factors related to sudden cardiac death (SCD), focusing on specific gene variations in patients with implantable cardioverter-defibrillators (ICDs).
- In the DISCOVERY trial, seven single-nucleotide polymorphisms (SNPs) in genes related to G-proteins were analyzed, revealing significant associations of two SNPs in the GNAS gene with ventricular tachyarrhythmia (VT).
- These findings were further validated in a larger community-based group, showing that the identified SNPs may predict increased risks for both VT and SCD.
We describe a case of a 63 year-old male who underwent successful RF ablation of recurrent ventricular tachycardia using epicardial approach.
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