Total thyroidectomy is associated with increased prevalence of permanent hypoparathyroidism.

Background: Thyroid disorders are very common in adults. Despite advances in conservative management, surgery remains a treatment modality of choice in many cases. The mortality and morbidity of thyroidectomy are low, but long-term postoperative hypoparathyroidism (HPT) remains a prominent complication of the procedure.

[Iodine supply and thyroid function in the group of healthy pregnant women living in Warsaw].

Unlabelled: Iodine deficiency and thyroid gland disorders are especially harmful for pregnant women and normal fetal development. After initiation in 1997 of obligatory iodine prophylaxis, Poland has been found since 2003 a country with sufficient delivery of this microelement. However, in the population of pregnant women, slight deficiency of this element still exists.

Insulin-like factor 3 -- a new hormone related to polycystic ovary syndrome?

Introduction: The aim of this study was to find a correlation between insulin-like factor 3 (INSL3) and androgens: androstenedione (A), free testosterone (fT), and total testosterone (T), in two groups of polycystic ovary syndrome (PCOS) women: those with a body mass index (BMI) lower than 25 kg/m(2) and those with a BMI higher than 25 kg/m(2). The association between INSL3 and other serum parameters: luteinising hormone (LH), follicle-stimulating hormone (FSH), dehydroepiandrosterone sulphate (DHEA-S), sex hormone binding globulin (SHBG) and glucose and insulin were also investigated.

Material And Methods: The study group comprised 37 PCOS women aged 27 ± 4 years.

Measuring salivary androgens as a useful tool in the diagnosis of polycystic ovary syndrome.

Introduction: Polycystic ovary syndrome (PCOS) is one of the commonest endocrinopathies. Clinically it can present as oligo-/amenorrhoea, hyperandrogenism and/or fertility problems.

Material And Methods: The study involved 60 women admitted to the Department of Internal Medicine and Endocrinology at the Medical University of Warsaw.

Thyroid-associated orbitopathy in patients with Hashimoto's thyroiditis: a case report.

Thyroid-associated orbitopathy is a set of ophthalmic symptoms resulting from an autoimmune process in which the swelling of extraocular tissues leads to exophthalmos either caused by hypersecretion and accumulation of glycosaminoglycans in the orbit fibroblasts or being the result of inflammatory processes in the oculomotor. These changes cause eyeball motility disturbances, keratopathy, and the pressure on the optical nerve. Thyroid-associated orbitopathy accompanies Graves' disease in most cases, whereas the Hashimoto's disease in only 5%.

Allotransplantation of cultured parathyroid progenitor cells without immunosuppression: clinical results.

Background: Hypoparathyroidism is a well-known consequence of extensive thyroid and parathyroid surgery. Allotransplantation of cultured parathyroid cells can be considered as an alternative to vitamin D3 and calcium supplementation in treatment of hypoparathyroidism. We present the long-term allotransplant activity in 85 patients who had undergone cellular allotransplantation for surgical hypoparathyroidism.

[Effectiveness of iodine prophylaxis in hypertensive patients on salt restricted diet].

Background: Iodine prophylaxis in Poland started in 1935 however it has been interrupted during Second World War, and also in 1980. In January 1997 a new approach of preventing iodine deficiency was introduced as obligatory iodination model of household salt to be extent of 30 mg KI/kg. The aim of the study was to determine iodine intake after introduction of mandatory salt iodization in group of persons being on low salt diet because of hypertension.

[Diagnostic difficulties in Grave's orbitopathy--case report].

Graves' orbitopathy is caused by intraorbital inflammatory reaction due to autoimmune thyroid disease. In most cases the diagnosis is based on the coexistence of typical eye signs and hyperthyroidism symptoms. In presented case, the absence of thyroid dysfunction implicated performance of differential diagnosis.

[Iodine supply in school children three years after introduction of obligatory salt iodization].

Three years after introduction of obligatory salt iodization in Poland we evaluated iodine supply in children from Mazovia region. Urinary iodine concentration (UIC) was estimated in morning samples from 779 schoolchildren aged 6-14 years. Previous investigation 7 years ago revealed mild or moderate iodine deficiency in this area.

[Diagnosis and treatment of thyroid nodules].

The paper presents current diagnostic and therapeutic approach of thyroid nodules. TSH and iodine are the main goitrogenic agents, but there are also other auto- para-endocrinal factors that play very important roles in goiter growth as well as in the intrinsic growth potential of some thyroid follicular cells. The diagnosis of thyroid nodule demands further investigation such as thyroid function evaluation and distinction between benign from malignant nodules using FNAB.

Salt iodination as a effective method of iodine supplementation.

Background: In January 1997 a new approach to preventing iodine deficiency was introduced in Poland. The goal of the present study was to determine whether the mandatory iodization of kitchen salt (30 mg KI/kg) has had any impact on ioduria.

Material/methods: The study was performed on 29 healthy volunteers, aged 22-29 (average age 23.