Limb Symmetry Index in Collegiate Dancers Using the Modified Star Excursion Balance Test and Single Leg Hops.

Dance is physically demanding and often involves unilateral movements performed within a small base of support. Prior authors have reported that dancers use one leg preferentially over the other (ie, lower extremity asymmetry). Increased leg asymmetry-quantified using the Limb Symmetry Index (LSI), is associated with increased injury risk.

Lattice Realization of Complex Conformal Field Theories: Two-Dimensional Potts Model with Q>4 States.

The two-dimensional Q-state Potts model with real couplings has a first-order transition for Q>4. We study a loop-model realization in which Q is a continuous parameter. This model allows for the collision of a critical and a tricritical fixed point at Q=4, which then emerge as complex conformally invariant theories at Q>4, or even complex Q, for suitable complex coupling constants.

Hyperuniformity in the Manna Model, Conserved Directed Percolation and Depinning.

Hyperuniformity is an emergent property, whereby the structure factor of the density n scales as S(q)∼q^{α}, with α>0. We show that for the conserved directed percolation (CDP) class, to which the Manna model belongs, there is an exact mapping between the density n in CDP, and the interface position u at depinning, n(x)=n_{0}+∇^{2}u(x), where n_{0} is the conserved particle density. As a consequence, the hyperuniformity exponent equals α=4-d-2ζ, with ζ the roughness exponent at depinning, and d the dimension.

Hepatocellular adenomas with severe intra-abdominal bleeding, related to an underlying coagulation disorder: a case report.

Background: Hepatocellular adenoma is a rare benign liver tumor. Typically, hepatocellular adenomas are solitary and are found in young women who use estrogen-containing contraceptives. The occurrence of multiple hepatocellular adenoma has been linked to higher body mass index, and as the prevalence of overweight increases, multiple hepatocellular adenomas are seen more often.

Adapting Real-Time Lung Function Measurements for SARS-CoV-2 Infection Studies in Syrian Hamsters.

Pulmonary function examinations are critical to assess respiratory disease severity in patients. In preclinical rodent models of viral respiratory infections, however, disease is frequently evaluated based on virological, pathological and/or surrogate clinical parameters, which are not directly associated with lung function. To bridge the gap between preclinical and clinical readouts, we aimed to apply unrestrained whole-body plethysmography (WBP) measurements in a SARS-CoV-2 Syrian hamster challenge model.

Transcriptomic Analysis of Pubertal and Adult Virgin Mouse Mammary Epithelial and Stromal Cell Populations.

Conflicting data exist as to how mammary epithelial cell proliferation changes during the reproductive cycle. To study the effect of endogenous hormone fluctuations on gene expression in the mouse mammary gland, we performed bulk RNAseq analyses of epithelial and stromal cell populations that were isolated either during puberty or at different stages of the adult virgin estrous cycle. Our data confirm prior findings that proliferative changes do not occur in every mouse in every cycle.

Kinesiophobia in Injured Athletes: A Systematic Review.

Athletes have a high risk of injury. Kinesiophobia is a condition in which an individual experiences a fear of physical movement and activity after an injury occurs. Our purpose was to systematically review the literature about Kinesiophobia in athletes.

Aichivirus A1 replicates in human intestinal epithelium and bronchial tissue: Lung-gut axis?

The role of aichivirus A1 (AiV-A1) in acute gastroenteritis remains controversial and in vitro data illustrating its pathogenesis in suitable human models are scarce. Here, we demonstrate that AiV-A1 isolate A846/88 replicates in ApoA1- (absorptive) and Ki-67-positive (proliferative) enterocytes in stem cell-derived human small intestinal epithelium (HIE) as well as in patient biopsy samples, but not in any of the tested human cell lines. The infection did not result in tissue damage and did not trigger type I and type III interferon (IFN) signalling, whereas the control, human coxsackievirus B3 (strain Nancy), triggered both IFNs.

Impact of Attentional Focus on Dance Performance: A Critically Appraised Topic.

Clinical Scenario: Dancing is a demanding esthetic activity with dancers having an 85% annual injury incident rate when performing complex dance motor skills. Teachers and clinicians use a combination of external and internal attentional cues when teaching dancers motor skills and when working on rehabilitation programs with injured dancers, respectively. External attentional focus (ie, focusing on movement outcome) reportedly results in superior performance than internal attentional focus (ie, focus on body movements).

Female Collegiate Dancers' Physical Fitness across Their Four-Year Programs: A Prospective Analysis.

Dance is physically demanding, requiring physical fitness (PF) that includes upper body, lower body, core fitness, and balance for successful performance. Whether PF changes as dancers advance from when they enter (freshmen) to when they graduate from their collegiate program (seniors) is unclear. We prospectively compared collegiate dancers' freshman-to-senior PF.

Depinning in the quenched Kardar-Parisi-Zhang class. II. Field theory.

There are two main universality classes for depinning of elastic interfaces in disordered media: quenched Edwards-Wilkinson (qEW) and quenched Kardar-Parisi-Zhang (qKPZ). The first class is relevant as long as the elastic force between two neighboring sites on the interface is purely harmonic and invariant under tilting. The second class applies when the elasticity is nonlinear or the surface grows preferentially in its normal direction.

Depinning in the quenched Kardar-Parisi-Zhang class. I. Mappings, simulations, and algorithm.

Depinning of elastic systems advancing on disordered media can usually be described by the quenched Edwards-Wilkinson equation (qEW). However, additional ingredients such as anharmonicity and forces that cannot be derived from a potential energy may generate a different scaling behavior at depinning. The most experimentally relevant is the Kardar-Parisi-Zhang (KPZ) term, proportional to the square of the slope at each site, which drives the critical behavior into the so-called quenched KPZ (qKPZ) universality class.

Experimental Test of Sinai's Model in DNA Unzipping.

The experimental measurement of correlation functions and critical exponents in disordered systems is key to testing renormalization group (RG) predictions. We mechanically unzip single DNA hairpins with optical tweezers, an experimental realization of the diffusive motion of a particle in a one-dimensional random force field, known as the Sinai model. We measure the unzipping forces F_{w} as a function of the trap position w in equilibrium and calculate the force-force correlator Δ_{m}(w), its amplitude, and correlation length, finding agreement with theoretical predictions.

Vimentin is required for tumor progression and metastasis in a mouse model of non-small cell lung cancer.

Vimentin is highly expressed in metastatic cancers, and its expression correlates with poor patient prognoses. However, no causal in vivo studies linking vimentin and non-small cell lung cancer (NSCLC) progression existed until now. We use three complementary in vivo models to show that vimentin is required for the progression of NSCLC.

Booster vaccination with Ad26.COV2.S or an Omicron-adapted vaccine in pre-immune hamsters protects against Omicron BA.2.

Since the original outbreak of the SARS-CoV-2 virus, several rapidly spreading SARS-CoV-2 variants of concern (VOC) have emerged. Here, we show that a single dose of Ad26.COV2.

Force Correlations in Disordered Magnets.

We present a proof of principle for the validity of the functional renormalization group, by measuring the force correlations in Barkhausen-noise experiments. Our samples are soft ferromagnets in two distinct universality classes, differing in the range of spin interactions, and the effects of eddy currents. We show that the force correlations have a universal form predicted by the functional renormalization group, distinct for short-range and long-range elasticity, and mostly independent of eddy currents.

Theory and experiments for disordered elastic manifolds, depinning, avalanches, and sandpiles.

Domain walls in magnets, vortex lattices in superconductors, contact lines at depinning, and many other systems can be modeled as an elastic system subject to quenched disorder. The ensuing field theory possesses a well-controlled perturbative expansion around its upper critical dimension. Contrary to standard field theory, the renormalization group (RG) flow involves a function, the disorder correlator Δ(), and is therefore termed the functional RG.

Continuous chromatin state feature annotation of the human epigenome.

Motivation: Segmentation and genome annotation (SAGA) algorithms are widely used to understand genome activity and gene regulation. These methods take as input a set of sequencing-based assays of epigenomic activity, such as ChIP-seq measurements of histone modification and transcription factor binding. They output an annotation of the genome that assigns a chromatin state label to each genomic position.

Functionals of fractional Brownian motion and the three arcsine laws.

Fractional Brownian motion is a non-Markovian Gaussian process indexed by the Hurst exponent H∈(0,1), generalizing standard Brownian motion to account for anomalous diffusion. Functionals of this process are important for practical applications as a standard reference point for nonequilibrium dynamics. We describe a perturbation expansion allowing us to evaluate many nontrivial observables analytically: We generalize the celebrated three arcsine laws of standard Brownian motion.

SigTools: exploratory visualization for genomic signals.

Motivation: With the advancement of sequencing technologies, genomic data sets are constantly being expanded by high volumes of different data types. One recently introduced data type in genomic science is genomic signals, which are usually short-read coverage measurements over the genome. To understand and evaluate the results of such studies, one needs to understand and analyze the characteristics of the input data.

Mean-field theories for depinning and their experimental signatures.

Mean-field theory is an approximation replacing an extended system by a few variables. For depinning of elastic manifolds, these are the position u of its center of mass and the statistics of the forces F(u). There are two proposals how to model the latter: as a random walk (ABBM model), or as uncorrelated forces at integer u (discretized particle model, DPM).

Randomized Controlled Trial Comparing Silver-Impregnated Fibrous Hydrocolloid Dressings With Silver Sulfadiazine Cream Dressings for the Treatment of Fracture Blisters to Determine Time to Surgical Readiness.

Objectives: To investigate, in patients with fracture blisters, the time to surgical readiness in those treated with silver-impregnated fibrous hydrocolloid (SFH) dressings compared with those treated with topical silver sulfadiazine (SS) cream and to determine the direct costs associated with both treatments.

Design: A single-blind, randomized controlled trial.

Setting: The study was conducted at Tygerberg Hospital, a tertiary care facility, and Worcester Provincial Hospital, a secondary care facility, Western Cape, South Africa.

Case Report of Traumatic Uterine Rupture in a Multigravida Woman with Emergency Department Cesarean Section.

Introduction: Uterine ruptures in blunt trauma are an extremely rare complication. Furthermore, while perimortem cesarean sections in cardiac arrest patients are a well-established practice in emergency medicine, cesarean sections in the emergency department are rarely performed on non-arresting patients.

Case Report: A multigravida woman at approximately 24 weeks gestation presented as a transfer from an outside hospital after a motor vehicle collision.

Extreme events for fractional Brownian motion with drift: Theory and numerical validation.

We study the first-passage time, the distribution of the maximum, and the absorption probability of fractional Brownian motion of Hurst parameter H with both a linear and a nonlinear drift. The latter appears naturally when applying nonlinear variable transformations. Via a perturbative expansion in ɛ=H-1/2, we give the first-order corrections to the classical result for Brownian motion analytically.