Assessing the Impact of Various Decontamination Instruments on Titanium and Zirconia Dental Implants: An In Vitro Study.

This study investigates the impact of various instrumentation techniques on material removal and surface changes in titanium (Ti)- and zirconia (Zr) implant discs. Ti- and Zr discs were subjected to standardized experiments using various instruments including airflow, ultrasound, carbide, and diamond burs. Instrumentation was performed for 60 s with continuous automatic motion.

Implant failure and clinical and radiographic outcomes after surgical treatment of peri-implantitis: A meta-analysis.

Purpose: To assess the implant failure rate and clinical and radiographic outcomes of implants affected by peri-implantitis that received surgical treatment.

Materials And Methods: A systematic search was conducted of three databases (PubMed, Embase and Cochrane Library) to identify studies that examined implant failure and biological outcomes after surgical peri-implantitis treatment, including ≥ 10 patients and reporting on a follow-up period of at least 12 months. Data and risk of bias were assessed qualitatively and quantitively.

Masticatory Muscles Activation and TMJ Space During Asymmetrically Loaded Jaw Closing.

Masticatory muscle activation and temporomandibular joint (TMJ) load generated during asymmetrically loaded jaw closing are largely unknown. Two different strategies were developed to explain how the central nervous system (CNS) generates muscle activation patterns during motion: minimization of joint load (MJL) vs. minimization of muscle effort (MME).

Clinical and histological wound healing patterns of collagen-based substitutes: An experimental randomized controlled trial in standardized palatal defects in humans.

Aim: To evaluate the progression of wound healing of standardized palatal defects in groups using three different collagen-based wound dressings and a control group, in terms of wound closure, pain perception and descriptive histology.

Materials And Methods: Twenty participants were enrolled in this experimental study, in whom four palatal defects were created. The defects (6 mm diameter, 3 mm depth) were randomly assigned to one of four treatment modalities: C (control), MG (Mucograft®), MD (mucoderm®) and FG (Fibro-Gide®).

4-Year Pulp Survival in a Randomized Trial on Direct Pulp Capping.

Introduction: This study aimed to assess pulp survival in a randomized trial on pulp lavage in adult nonpainful posterior teeth with carious pulp exposure. The treatment included complete caries excavation, direct pulp capping with mineral trioxide aggregate, and immediate restoration with composite resin.

Methods: Fluid was collected from the pulp wound to assess matrix metalloproteinase-9 (MMP-9) and total protein values.

Comparison of Geometric Accuracy of Low-Dose and Standard-Dose Dental CBCT Imaging Protocols in CAD/CAM-Guided Dental Implant Surgery.

Purpose: This preclinical comparison study assessed the diagnostic accuracy of low-dose CBCT protocols compared with standard-dose protocols in digital implant treatment planning and template-guided implant surgery.

Materials And Methods: Thirty mandibles of pig cadavers underwent both CBCT protocols on an Orthophos SL Unit (Dentsply-Sirona). Surface scans of the regions of interest were performed to create a digital diagnostic wax-up followed by 120 subsequent implant plannings (one implant per quadrant).

Bone defect development in experimental canine peri-implantitis models: a systematic review.

Purpose: To provide a systematic overview of preclinical research regarding bone defect formation around different implant surfaces after ligature-induced peri-implantitis models in dogs. Two focused questions were formulated: 'How much bone loss can be expected after a certain time of ligature induced peri-implantitis?' and 'Do different implant types, dog breeds and study protocols differ in their extent of bone loss?'

Materials And Methods: A systematic literature search was conducted on four databases (MEDLINE, Web of Science, EMBASE and Scopus). Observations, which consisted of bone defects measured directly after ligature removal in canine models, were included and analysed.

Buccal soft tissue dehiscence defects at dental implants-associated factors and frequency of occurrence: A systematic review and meta-analysis.

Aim: To identify the factors associated with buccal peri-implant soft tissue dehiscences (BSTDs) and their frequency of occurrence.

Materials And Methods: Randomized controlled trials, controlled clinical trials, cohort studies, and case series assessing the frequency of occurrence of BSTD were included. BSTD was defined as an apical migration of the peri-implant soft tissues of ≥1 mm from the baseline examination (final restoration) or in comparison with the adjacent or contralateral natural tooth.

Microbial approaches for the assessment of toothpaste efficacy against oral species: A method comparison.

Antibacterial properties of toothpastes enable chemical plaque control in limited-access tooth regions that are mechanically not sufficiently reached by toothbrushes. Therefore, this study aimed to compare different microbial methods to assess antimicrobial toothpaste properties and evaluate different toothpastes in terms of their antibacterial efficacy against different oral microorganisms in an in vitro setting. Six toothpaste suspensions with varying antibacterial supplements were applied to a multispecies biofilm model (Actinomyces oris, Candida albicans, Fusobacterium nucleatum, Streptococcus oralis, and Streptococcus mutans) as well as to each microorganism.

The OrBiD (Oral Health, Bite Force and Dementia) Pilot Study: A Study Protocol for New Approaches to Masticatory Muscle Training and Efficient Recruitment for Longitudinal Studies in People with Dementia.

Research with people with dementia is a great challenge in terms of recruitment, study participation and adherence to interventions resulting in less research activity and higher financial, organizational and personnel efforts. As dementia progresses, there is a deterioration in general and oral health and chewing function. Oral treatment options often focus on healthy patients.

Three-dimensional perception of cinematic rendering versus conventional volume rendering using CT and CBCT data of the facial skeleton.

The aim of this exploratory study is to analyse whether three-dimensional cinematic rendering image reconstructions offer advantages over conventional volume rendering in the visualisation of cone beam computed tomography (CBCT) and computed tomography (CT) images of the facial skeleton. This is of interest, as some information gets lost during the rendering process. This especially applies to structures in the background of the image and some surface information which can be lost.

Accuracy of augmented reality-assisted vs template-guided apicoectomy - an ex vivo comparative study.

Aim: The aim of the present ex vivo study was to examine the accuracy of augmented reality-assisted apicoectomies (AR-A) versus template-guided apicoectomies (TG-A).

Materials And Methods: In total, 40 apicoectomies were performed in 10 cadaver pig mandibles. Every pig mandible underwent two AR-A and two TG-A in molar and premolar teeth.

Efficacy and safety of P-4 for the treatment of periodontal defects in dogs.

Objectives: This study's aim was to investigate the safety and performance of a self-assembling peptide matrix (SAPM) P-4 for the treatment of periodontal disease in a controlled pre-clinical study.

Materials And Methods: Acute buccal bony dehiscence defects (LxW: 5 × 3 mm) were surgically created on the distal root of four teeth on one mandible side of 7 beagle dogs followed by another identical surgery 8 weeks later on the contralateral side. SAPM P-4 (with and without root conditioning with 24% EDTA (T1, T2)), Emdogain® (C) and a sham intervention (S) were randomly applied on the four defects at each time point.

Diagnostic Accuracy of Cystic Lesions Using a Pre-Programmed Low-Dose and Standard-Dose Dental Cone-Beam Computed Tomography Protocol: An Ex Vivo Comparison Study.

Background: This study aimed to analyze the diagnostic reliability of radiographic assessment of cystic lesions using a pre-set, manufacturer-specific, low-dose mode compared to a standard-dose dental cone-beam computed tomography (CBCT) imaging protocol.

Methods: Forty pig mandible models were prepared with cystic lesions and underwent both CBCT protocols on an Orthophos SL Unit (Dentsply-Sirona, Bensheim, Germany). Qualitative and quantitative analysis of CBCT data was performed by twelve investigators independently in SIDEXIS 4 (Dentsply-Sirona) using a trial-specific digital examination software tool.

Effect of Caries Infiltrant on Margin Integrity of Composite Fillings Placed Adjacent to Demineralised Primary Enamel.

Purpose: To investigate the influence of pretreating demineralised enamel with an infiltrant on the margin integrity of Class V like composite restorations on primary teeth bonded with different adhesives.

Materials And Methods: Forty specimens from primary molars were demineralised and circular class-V-like cavities were prepared. The cavities were treated with a universal adhesive (Scotchbond Universal Adhesive, 3M Oral Care), applied either in self-etch (SE) or etch-and-rinse mode (ER) mode.

The effect of clinical education on optimizing self-care by dental students in Switzerland.

Students, who may begin their dental education with sub-optimal oral self-care practices, are taught they should motivate patients to clean interdentally and reduce/stop smoking. To better understand their internalization of these concepts, students were surveyed at two distinct time points. Student cohorts from four Swiss universities were asked to complete an interdental cleaning/smoking habit questionnaire at the beginning of their pre-clinical education (n = 110) and again a year later, when beginning treatment of patients (n = 115).

MMP-9 Levels and NaOCl Lavage in Randomized Trial on Direct Pulp Capping.

Outcome expectations of direct pulp capping in carious teeth are obscured by a clinically unknown infiltration and breakdown of the dental pulp tissue. Histologic studies showed that this soft tissue breakdown is related to the innate immune system. We hypothesized 1) that a neutrophil biomarker could predict the outcome of direct pulp capping and 2) that using sodium hypochlorite (NaOCl) as a lavage solution to remove necrotized infected pulp tissue could improve it.

Clinical outcomes of all-ceramic single crowns and fixed dental prostheses supported by ceramic implants: A systematic review and meta-analyses.

Objective: To analyze the clinical outcomes of all-ceramic single crowns (SCs) and fixed dental prostheses (FDPs) supported by ceramic implants.

Materials And Methods: Based on a focused question and customized PICO framework, electronic (Medline/EMBASE/Cochrane) and manual searches for studies reporting the clinical outcomes of all-ceramic SCs and FDPs supported by ceramic implants ≥12 months were performed. The primary outcomes were reconstruction survival and the chipping proportion.

Short- and Long-Term Dentin Bond Strength of Bioactive Glass-Modified Dental Adhesives.

This study investigated the short- and long-term effects of dental adhesives doped with nano-sized bioactive glass 45S5 (BAG) on the resin-dentin interfacial bond strength. Two etch-and-rinse adhesives (Adper Scotchbond Multi-Purpose (ASB) and Solobond Plus (SB)) and one self-etch adhesive (Clearfil SE Bond (CF)) were doped with different concentrations of BAG (5, 10, and 20 wt%). The unmodified (0 wt% BAG) commercial adhesives served as control groups.

Origin of MMP-8 and Lactoferrin levels from gingival crevicular fluid, salivary glands and whole saliva.

Background: Pathologically elevated levels of matrix metalloproteinase-8 (MMP-8) and Lactoferrin in oral fluids have been associated with the presence of gingivitis/periodontitis. This study aimed to assess the origin of MMP-8 and Lactoferrin in periodontitis patients and to identify the degree to which conventional clinical parameters correlate with their presence.

Methods: A total of ten periodontitis and ten healthy patients were included in this study.

A systematic review on the effect of inorganic surface coatings in large animal models and meta-analysis on tricalcium phosphate and hydroxyapatite on periimplant bone formation.

The aim of the present systematic review was to analyse studies using inorganic implant coatings and, in a meta-analysis, the effect of specifically tricalcium phosphate (TCP) and hydroxyapatite (HA) implant surface coatings on bone formation according to the PRISMA criteria. Inclusion criteria were the comparison to rough surfaced titanium implants in large animal studies at different time points of healing. Forty studies met the inclusion criteria for the systematic review.

Final Posttreatment Occlusion in Patients With Unilateral Cleft Lip and Palate.

Objective: To evaluate final posttreatment occlusion in patients with complete unilateral cleft lip and palate (cUCLP) by comparing (1) 3 treatment centers, (2) males and females, (3) cleft and noncleft sides, (4) right- and left-sided clefts, and (5) orthodontic treatment with/without orthognathic surgery (OS).

Design: Retrospective cohort study.

Patients: Blinded posttreatment dental casts of 56 patients (19.

Time Efficiency of Digitally and Conventionally Produced Single-Unit Restorations.

The purpose of this in vitro study was to compare the time efficiency of digital chairside and labside workflows with a conventional workflow for single-unit restorations. The time efficiency in this specific sense was defined as the time, which has to be spent in a dental office by a dental professional performing the relevant steps. A model with interchangeable teeth on position 36 was created.

Potential of different fluoride gels to prevent erosive tooth wear caused by gastroesophageal reflux.

Background: This in-vitro-study aimed to evaluate the potential of different fluoride gels to prevent gastroesophageal reflux induced erosive tooth wear.

Methods: Surface baseline profiles of a total of 50 bovine enamel specimens [randomly assigned to five groups (G1-5)] were recorded. All specimens were positioned in a custom made artificial oral cavity and perfused with artificial saliva (0.

Oral Diagnostic Methods for the Detection of Periodontal Disease.

Periodontitis is a common immune-inflammatory oral disease. Early detection plays an important role in its prevention and progression. Saliva is a reliable medium that mirrors periodontal health and is easily obtainable for identifying periodontal biomarkers in point-of-care diagnostics.