Publications by authors named "Widya Saraswati"
Objectives: Calcium carbonate (CaCO), a major inorganic component in bones and teeth, offers potential protection against demineralization. This study investigates the effect of CaCO from shells on the expression of fibroblast growth factor 2 (FGF2), transforming growth factor-β1 (TGF-β1), and collagen type 1 in the rat dental pulp.
Materials And Methods: The first maxillary molars of were perforated and subsequently pulp capped with CaCO extracted from shells.
Background: Finding a new natural scaffold is challenging due to crucial impact on long-term treatment outcomes in pulp capping. In this context, nano hydroxyapatite (nano-HA) is a potential candidate having similar properties to bone tissue in the body. The compound is often synthesized with Epigallocatechin-3-gallate (EGCG) which offers anti-inflammatory and antibacterial properties.
View Article and Find Full Text PDFCaCO from shell as reparative dentin inducer in odontoblast pulp cells: In-vivo study.
J Oral Biol Craniofac Res
January 2023
Introduction: (blood clam) shell contained 98.7% of calcium carbonate (CaCO). This material has bio-properties that able to induced the dentin regeneration.
View Article and Find Full Text PDFArticle Synopsis
- The study aimed to analyze inflammation in the dental area of diabetic rats by measuring the expression of interleukin 6 (IL-6) and tumor necrosis factor α (TNF-a) after inducing apical periodontitis with lipopolysaccharide (LPS).
- Fifteen diabetic rats were created using streptozotocin, and apical periodontitis was induced; the rats were then divided into three groups for observation at 14, 28, and 42 days post-induction.
- Results showed a significant increase in IL-6 and TNF-a expression over time, particularly noting a major rise in IL-6 at 42 days, while TNF-a levels were notably elevated after just