Publications by authors named "Widowati Siswomihardjo"

The use of biogenic calcium ions for the source of hydroxyapatite (HAp or HA) are very common and have been being explored extensively. However, it usually results high crystalline HA, due to high reaction and decomposition temperatures. In this study, strontium (Sr) doped HA from the golden apple snail shells (Pomacea canaliculate L) was successfully synthesized.

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Background: Synthetic fibers have many benefits in clinical practice; however, they cause microplastic pollution, and their unaffordable price increases treatment costs. Natural silk fibers require biocompatibility assessment. This study investigated the effects of natural and synthetic fiber-reinforced composites (FRCs) on the cytotoxicity of fibroblast cell lines.

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A scaffold that replicates the physicochemical composition of bone at the nanoscale level is a promising replacement for conventional bone grafts such as autograft, allograft, or xenograft. However, its creation is still a major challenge in bone tissue engineering. The fabrication of a fibrous PVA-HA/Sr matrix made of strontium (Sr)-substituted hydroxyapatite from the shell of L.

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Objectives: To evaluate the biocompatibility and mechanical properties of experimental -phenol-A and -GMA free E-glass fiber-reinforced composites (FRCs) prepared with hexanediol dimethacrylate (HDDMA) based resin.

Methods: Two ratios of HDDMA/TEGDMA resin were evaluated: exp-1 (70/30 wt.%) and exp-2 (50/50 wt.

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Objectives. The aim of this paper was to evaluate the cytotoxicity of Indonesian silkworm cocoon extract of Cricula triphenestrata on human fibroblasts. Methods and Materials.

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Synthetic hydroxyapatite (HA) has been widely used and developed as the material for bone substitute in medical applications. The addition of zirconia is needed to improve the strength of hydroxyapatite as the bone substitute. One of the drawbacks in the use of biomedical materials is the occurrence of biomaterial-centred infections.

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This study evaluates effects of aging on repair bond strengths of microhybrid, nanohybrid, and nanofilled composite resins and characterizes the interacting surfaces after aging. Disk-shaped composite specimens were assigned to one of three aging conditions: (1) thermocycling (5,000 ×, 5-55 °C), (2) storage in water at 37 °C for 6 months, or (3) immersion in citric acid at 37 °C, pH 3 for 1 week; a non-aged group acted as the control. Two surface conditionings were selected: intermediate adhesive resin application (IAR-application) and chairside silica coating followed by silanization and its specific IAR-application (SC-application).

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Objectives: To evaluate immediate repair bond strengths and failure types of resin composites with and without surface conditioning and characterize the interacting composite surfaces by their surface composition and roughness.

Methods: Microhybrid, nanohybrid and nanofilled resin composites were photo-polymerized and assigned to four groups: (1) no conditioning (Control), (2) no conditioning, polymerized against a Mylar strip (Control, with strip), (3) intermediate adhesive resin (IAR) application, and (4) chair-side silica coating, silanization and intermediate resin application (SC). Resin composites, similar as their substrates, were adhered onto the substrates.

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