Publications by authors named "Wichai Aekplakorn"

Article Synopsis
  • The Asia-Pacific region faces a significant challenge with obesity, which is linked to various health issues and rising medical costs; a hypothetical 10% weight loss could lead to significant savings over the next decade.
  • Using an epidemiological-economic model, the study assessed current and future obesity-related health costs and problems in Australia, South Korea, Thailand, and India, revealing that costs could increase dramatically if no action is taken.
  • A 10% weight reduction could save billions in medical expenses by 2032 while reducing the incidence of obesity-related comorbidities, highlighting the need for effective policies to support obesity management in the region.
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Background: Excessive sodium intake is associated with high blood pressure and an increased risk of cardiovascular disease. However, reducing dietary salt has been challenging due to a lack of awareness and a high threshold in detecting saltiness.

Objectives: The goal of this study is to evaluate the effectiveness of a combined intervention (intensive dietary education, food reformulation, environmental changes to facilitate salt reduction, and salt meter utilization), in comparison to standard education only, on salt intake and blood pressure.

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  • Thailand's universal health coverage provides free hypertension treatment, yet the prevalence of hypertension remains high, with 25.7% of adults affected as of 2019-2020.
  • Although awareness and treatment of hypertension improved until 2014, they have declined since then, with only 51.5% aware of their condition and just 22.7% achieving controlled blood pressure.
  • The findings highlight the need for a stronger public health response in Thailand to address the stagnation in awareness and the recent decrease in blood pressure control, aiming to prevent cardiovascular diseases.
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  • This study investigated how well four noninvasive body measurement methods can predict diabetes and hypertension risk in the Lao population using data from a national health survey involving 3,240 adults aged 18 and older.
  • Among the tested indices, the waist-to-height ratio (WHtR) showed the strongest predictive ability for both diabetes (AUC = 0.73) and hypertension (AUC = 0.70), making it effective for various settings, including urban and rural areas.
  • The WHtR can be utilized as a reliable screening tool for public health and clinical purposes in Laos, with an optimal threshold of 0.5 applicable across different sexes, ages, and ethnic groups.
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Article Synopsis
  • Geriatric syndrome (GS) encompasses common health issues like functional decline, cognitive impairment, and frailty among older adults, significantly impacting individuals and the healthcare system.
  • This study analyzed data from 7,365 older individuals in Thailand to explore socioeconomic inequalities related to GS, focusing on a wealth index and various sociodemographic factors.
  • Findings revealed that GS phenotypes disproportionately affect poorer elderly individuals, and work status plays a role in creating more equitable health distributions, suggesting a need for targeted health policies in Thailand.
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Wilson's disease (WD) is a rare metabolic disorder caused by variations in the ATP7B gene. It usually manifests hepatic, neurologic, and psychiatric symptoms due to excessive copper accumulation. The prevalence of WD and its common variants differ across populations.

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Rationale: A small number of earlier studies have suggested an effect of temporary abstinence campaigns on alcohol consumption. However, all were based on self-reported consumption estimates.

Objectives: Using a time series of 23-year monthly alcohol sales data, this study examined the effect of an annual temporary abstinence campaign, which has been organised annually since 2003 during the Buddhist Lent period (spanning 3 months), on population-level alcohol consumption.

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Patients with metabolic dysfunction-associated fatty liver disease (MAFLD) often present with concomitant metabolic dysregulation and alcohol consumption, potentially leading to distinct clinical outcomes. We analyzed data from 8043 participants with MAFLD in the Thai National Health Examination Survey with linked mortality records. According to the MAFLD criteria, 1432 individuals (17.

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In this cross-sectional random survey among Thai adults living in Bangkok, we aimed to identify the prevalence of hearing problems and examine their relationship with individual factors. We administered a self-report questionnaire and performed pure-tone air conduction threshold audiometry. A total of 2463 participants (1728 female individuals) aged 15-96 years were included.

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Objectives: X chromosome has been considered as a risk factor for SLE, which is a prototype of autoimmune diseases with a significant sex difference (female:male ratio is around 9:1). Our study aimed at exploring the association of genetic variants in X chromosome and investigating the influence of trisomy X in the development of SLE.

Methods: X chromosome-wide association studies were conducted using data from both Thai (835 patients with SLE and 2995 controls) and Chinese populations (1604 patients with SLE and 3324 controls).

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Death and end-stage kidney disease (ESKD) are major outcomes of glomerular disease. (GD) The years of potential life lost (YLL) may provide additional insight into the disease burden beyond death rates. There is limited data on premature mortality in GD.

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Background & Aims: Studies have determined that people with genetically defined lactase non-persistence have lower dairy intake that may lead to an increase risk of various non-communicable diseases. Furthermore, lactase non-persistence itself has been associated with insulin resistance. However, data on lactase non-persistence status and dairy intake in developing countries are sparse.

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Objective: The prevalence of vitamin D deficiency worldwide remains unknown. In the Thai 4th National Health Examination Survey (2008-2009) cohort, ∼45% and 7% of the adult population had serum 25-hydroxyvitamin-D [25(OH)D] levels below the threshold of 75 and 50 nmol/L, respectively. Vitamin D has been a hot topic in the scientific community.

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Objectives: This study aimed to examine cigarette use distribution, pattern of e-cigarette use and to determine socioecological model (SEM) factors associated with e-cigarette use among Thai youth (aged 15-24).

Design: An institution-based cross-sectional study.

Participants: The study conducted in five regions: the north, south, central, northeast and Bangkok area of Thailand from May to October 2021.

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Background: Helminthiases are highly endemic in Southeast Asia, including the Lao People's Democratic Republic (Lao PDR). This study aimed to assess the current intestinal helminth infections and the associated risk factors among adults across the Lao PDR.

Methods: A cross-sectional survey was conducted in 165 villages across 17 provinces and the Vientiane Capital, Lao PDR.

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Background: Extended life spans have led to an increase in the number of older people and an increase in the prevalence of disability among people older than 60 years of age.

Objective: This study aims to investigate the association of sociodemographic variables and unhealthy behaviors with limitations in activities of daily living (ADL) among Thai older adults. The study also projects the number of older individuals likely to experience ADL limitations in the next 20 years.

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Objective: To examine the association between dietary diversity (DD) and mortality among Thai older people and to investigate whether age, sex, and nutritional status modify this association.

Methods: The national survey conducted from 2013 to 2015 recruited 5631 people aged >60 years. Dietary diversity score (DDS) was assessed for the consumption of eight food groups using food frequency questionnaires.

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The relationship of ideal cardiovascular health (CVH) and health outcomes has been rarely assessed in middle-income countries. We determined the ideal CVH metrics and association with all-cause and cardiovascular (CVD) mortality in the Thai population. We used baseline data from two rounds of the National Health Examination survey (15,219 participants in 2009 and 14,499 in 2014), and assessed all-cause and CVD deaths until 2020.

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Background: Thailand has an ongoing action plan to reduce human immunodeficiency virus (HIV) discrimination and stigma. We aimed to monitor the level of stigmatizing and discriminatory attitudes toward people living with HIV/AIDS (PLWHA) among the general adult population and to investigate its related factors.

Methods: This study was based on data from the 6 Thai National Health Examination Survey, a large-scale country-wide survey in 2019-2020.

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Background: Frailty has been increasingly recognized as a public health problem for aging populations with significant social impact, particularly in low- and middle-income countries. We aimed to develop a modified version of the Thai Frailty Index (TFI) and explore the association between different frailty statuses, socioeconomic factors, and mortality in community-dwelling older people from a middle-income country.

Methods: The data from participants aged ≥60 years in the Fourth Thai National Health Examination Survey were used to construct the 30-item TFI.

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Introduction: Depression and e-cigarette use among adolescents are two health burdens. However, the association between these dual problems have been less studied, especially in low- and middle-income countries. This study examined the association between depression and e-cigarette use among adolescents in Thailand.

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Background: Sleep duration has been proposed to be associated with high blood pressure. However, nationwide studies regarding this association in adolescents remain limited. This study aimed to explore the national prevalence of high blood pressure among Thai adolescents and to determine the association between sleep duration and high blood pressure.

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Background: Cardiovascular diseases (CVD) are the common comorbidities in older people. Healthy diet is an essential strategy to alleviate the risk of developing CVD. Dietary diversity (DD) is an indicator of diet quality.

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