Publications by authors named "Whitney Booker"
Objectives: Traditionally, midline vertical skin incisions have been utilized during surgery for placenta accreta spectrum (PAS), as it is considered to maximize exposure and allow for a uterine incision to avoid the placenta. However, literature directly comparing outcomes of vertical versus transverse incisions in PAS is sparse. Our objective was to compare maternal outcomes between patients who underwent a vertical versus a transverse skin incision for PAS.
View Article and Find Full Text PDFObjective: In this study, we piloted the use of continuous 24-hour blood pressure (BP) monitoring in postpartum patients with preeclampsia with severe features.
Study Design: We measured continuous BP for up to 24 hours using finger plethysmography. We also used an oscillometric device to measure brachial BP per usual clinical protocol (intermittent BP) during the same monitoring period.
Objective: This study aimed to compare the effectiveness of oral short-acting (SA) nifedipine with intravenous (IV) labetalol for the treatment of postpartum (PP) severe hypertension.
Study Design: We conducted a retrospective cohort study of women who delivered at a tertiary care facility between January and December 2018, had not previously received antihypertensive medication, and required treatment for PP severe hypertension defined as systolic blood pressure (SBP) ≥ 160 mm Hg and/or diastolic blood pressure (DBP) ≥110 mm Hg. Exposure groups were defined by the receipt of either oral SA nifedipine or IV labetalol.
Background: Preeclampsia is associated with autonomic dysregulation during pregnancy; however, less is known about autonomic function in the first week postpartum after preeclampsia.
Methods: We retrospectively analyzed data from a prospective cohort of women with and without preeclampsia. Continuous blood pressure and heart rate were measured with finger plethysmography within 7 days postpartum.
Article Synopsis
- - The study aimed to identify clinical risk factors and obstetric complications from a woman's first delivery that could lead to severe morbidity or transfusion during a second delivery hospitalization in New York State from 2010 to 2017.
- - The researchers analyzed data from 624,500 delivery hospitalizations, finding that 0.85% of second deliveries experienced severe maternal morbidity, with significant factors including severe morbidity and transfusion during the first delivery, alongside conditions like pregestational diabetes.
- - The conclusion highlighted that complications identified in the first delivery strongly predict severe morbidity in a second delivery, with severe maternal morbidity from the first delivery posing the highest risk.
In 2021, the severe acute respiratory syndrome coronavirus 2 Delta variant rapidly proliferated and became dominant. Some but not all research evidence supports that Delta was associated with increased maternal risk. The purpose of this study was to determine whether Delta was associated with risk for cardiac and respiratory complications in a national sample.
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- The study analyzed trends and risk factors related to antenatal pyelonephritis hospitalizations in the US from 2010 to 2020.
- A total of 49,140 out of 10.2 million delivery hospitalizations involved antenatal pyelonephritis, showing a 29% decrease in associated admissions over the decade.
- Despite this decline, there has been an increase in the risk of sepsis and severe maternal morbidity during these hospitalizations, indicating potential concerns for maternal health.
The coordinated biomechanical performance, such as uterine stretch and cervical barrier function, within maternal reproductive tissues facilitates healthy human pregnancy and birth. Quantifying normal biomechanical function and detecting potentially detrimental biomechanical dysfunction (e.g.
View Article and Find Full Text PDFObjective: The American College of Obstetrics threshold for hypertension (≥140/90 mm Hg) differs from those of the American College of Cardiology (ACC) and the American Heart Association (AHA). It is unknown if ACC/AHA hypertension levels are associated with adverse pregnancy outcomes (APOs) after 20 weeks gestation. The purpose of this study is to analyze APOs in women with blood pressure (BP) in the elevated or stage 1 range after 20 weeks gestation.
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- Intracerebral hemorrhage (ICH) poses significant risks during and after pregnancy, with a study examining its characteristics in pregnant individuals compared to nonpregnant adults.
- Among 134 young adults analyzed, 19% experienced pregnancy-associated ICH (P-ICH), primarily occurring in the postpartum period, and P-ICH showed a higher likelihood of being primary (spontaneous) compared to nonpregnant women.
- Despite lower in-hospital mortality rates for P-ICH patients (4%) versus nonpregnant women (13%) and men (24%), a quarter of P-ICH patients were left bedbound or dependent upon discharge, indicating serious functional impairments.
Objective: To evaluate risk for adverse obstetric outcomes associated with the coronavirus disease 2019 (COVID-19) pandemic period and with COVID-19 diagnoses.
Design: Serial cross-sectional study.
Setting: A national sample of US delivery hospitalisations before (1/2016 to 2/2020) and during the first 10 months of (3/2020 to 12/2020) the COVID-19 pandemic.
Objective: To evaluate risk for peripartum cardiomyopathy during delivery and postpartum hospitalizations, and analyze associated trends, risk factors, and clinical outcomes.
Methods: The 2010-2020 Nationwide Readmissions Database was used for this retrospective cohort study. Delivery hospitalizations along with postpartum readmissions occurring within five months of delivery discharge were analyzed.
Background: Although peripartum hysterectomy for placenta accreta spectrum disorder is known to be associated with complications at the time of delivery, there are limited data on postpartum outcomes and readmission risk in this population.
Objective: This study aimed to analyze risks for adverse outcomes and postpartum readmissions in the setting of peripartum hysterectomy for placenta accreta spectrum disorder by severity of placenta accreta spectrum disorder subcategory.
Study Design: Using the 2016-2020 Nationwide Readmissions Database, this retrospective cohort study identified peripartum hysterectomies with a diagnosis of placenta accreta spectrum disorder.
Objective: Given that updated estimates of Ehlers-Danlos syndrome and risks for obstetric complications including postpartum readmission may be of public health significance, we sought to analyze associated obstetric trends and outcomes in a nationally representative population.
Study Design: The 2016 to 2020 Nationwide Readmissions Database was used for this retrospective cohort study. Delivery hospitalizations to women aged 15 to 54 with and without Ehlers-Danlos syndrome were identified.
Article Synopsis
- * Using data from the National Inpatient Sample, the research showed a rise in SLE cases from 6.7 to 14.6 per 10,000 delivery hospitalizations, indicating a significant average annual increase of 4.5%.
- * Women with SLE experienced higher rates of severe complications, such as non-transfusion morbidity and preterm delivery, highlighting the increasing challenges associated with these conditions during pregnancy.
Article Synopsis
- The study investigates how changes in dynamic cerebral autoregulation (DCA) affect mothers after experiencing severe preeclampsia postpartum, compared to healthy postpartum and non-pregnant women.
- Researchers used techniques like transcranial Doppler and blood pressure monitoring to measure DCA parameters within a week of delivery in these groups.
- Results indicated that postpartum participants showed faster autoregulatory responses but with impaired dampening effects, suggesting a hyperdynamic state in DCA regardless of preeclampsia status.
Postpartum stroke trends, risk factors, and associated adverse outcomes.
Am J Obstet Gynecol MFM
May 2023
Article Synopsis
- Management of postpartum stroke has seen quality improvement efforts, but there's a lack of recent national data on readmissions.
- This study used the Nationwide Readmissions Database from 2013 to 2019 to analyze trends, risk factors, and complications related to postpartum stroke readmissions within 60 days after discharge.
- Results showed that out of over 21 million deliveries, 5,006 had stroke readmissions, with no significant change in overall readmission rates, while risk factors like preeclampsia were linked to higher odds of readmission.
Article Synopsis
- The study investigates the prevalence and outcomes of obstructive sleep apnea (OSA) among pregnant women in the U.S. during hospital deliveries from 2000 to 2019, revealing a significant increase in cases over the years.
- Out of over 76 million delivery hospitalizations analyzed, only 54,238 (0.07%) were diagnosed with OSA, but the rate jumped from 0.4 to 20.5 cases per 10,000 over the study period, indicating a concerning trend.
- Key clinical factors linked to OSA included obesity, asthma, chronic hypertension, and pregestational diabetes, with the presence of OSA associated with higher risks for serious complications, such as mechanical ventilation, acute respiratory
Background: Up-to-date data on population-level risk factors for postpartum psychosis is limited, although increasing substance use disorders, psychiatric disorders, autoimmune disorders, and other medical comorbidities in the obstetrical population may be contributing to the increased baseline risk of postpartum psychosis.
Objective: This study aimed to determine trends in and risk factors for postpartum psychosis during delivery hospitalizations and postpartum readmissions.
Study Design: Analyzing the 2016-2019 Nationwide Readmission Database, this repeated cross-sectional study identified diagnoses of postpartum psychosis during delivery hospitalizations and postpartum readmissions within 60 days of discharge.
Objective: To determine whether longitudinal health data accounts for end-organ injury or death in the setting of chronic hypertension.
Design: Cohort of 64 799 deliveries to 61 854 women.
Setting: US claims data for the preiod 2008-2019.
Importance: The Mediterranean diet pattern is inversely associated with the leading causes of morbidity and mortality, including metabolic diseases and cardiovascular disease, but there are limited data on its association with adverse pregnancy outcomes (APOs) among US women.
Objective: To evaluate whether concordance to a Mediterranean diet pattern around the time of conception is associated with lower risk of developing any APO and individual APOs.
Design, Setting, And Participants: This prospective, multicenter, cohort study, the Nulliparous Pregnancy Outcomes Study: Monitoring Mothers-to-Be, enrolled 10 038 women between October 1, 2010, and September 30, 2013, with a final analytic sample of 7798 racially, ethnically, and geographically diverse women with singleton pregnancies who had complete diet data.
Background: The utility of prophylactic endovascular internal iliac balloon placement in the surgical management of placenta accreta spectrum is debated.
Objective: In this study, we review outcomes of surgical management of placenta accreta spectrum with and without prophylactic endovascular internal iliac balloon catheter use at a single institution.
Study Design: This is a retrospective cohort study of consecutive viable singleton pregnancies with a confirmed pathologic diagnosis of placenta accreta spectrum undergoing scheduled delivery from October 2018 through November 2020.