. Image reconstruction is a fundamental step in magnetic particle imaging (MPI). One of the main challenges is the fact that the reconstructions are computationally intensive and time-consuming, so choosing an algorithm presents a compromise between accuracy and execution time, which depends on the application.
View Article and Find Full Text PDFAdvances in instrumentation and tracer materials are still required to enable sensitive, accurate, and localized in situ 3D temperature monitoring by magnetic particle imaging (MPI). We have developed a high-resolution magnetic particle imaging instrument and implemented a low-noise multi-harmonic lock-in detection method to observe and quantify temperature variations in iron oxide nanoparticle tracers using the harmonic ratio method for determining temperature. Using isolated harmonics for MPI and temperature imaging revealed an apparent dependence of imaging resolution on harmonic number.
View Article and Find Full Text PDFCharacterization of the magnetization dynamics of single-domain magnetic nanoparticles (MNPs) is important for magnetic particle imaging (MPI), magnetic resonance imaging (MRI), and emerging medical diagnostic/therapeutic technologies. Depending on particle size and temperature, nanoparticle magnetization relaxation time constants span from nanoseconds to seconds. In solution, relaxation occurs via coupled Brownian and Néel relaxation mechanisms.
View Article and Find Full Text PDFMagnetic nanoparticle (MNP) thermometry based on magnetic particle spectroscopy (MPS) is explored as a potential approach for realizing in-situ temperature measurement of 3D objects. MNP thermometry relies on the nonlinear magnetization response to an AC drive field. This nonlinear response has functional dependence on frequency and temperature, governed by the complex magnetization dynamics of MNPs suspended in solution.
View Article and Find Full Text PDFJ Res Natl Inst Stand Technol
July 2018
The Minamata Convention on Mercury has created a near-term need to develop alternative fixed points to replace the mercury triple point (Hg TP) for calibration of standard platinum resistance thermometers (SPRTs) on the International Temperature Scale of 1990 (ITS-90). The sulfur hexafluoride (SF) TP is a good candidate to provide adequate "drop-in compatible" replacements for the lowest costs. We report our first results of SF TP realizations performed at the National Institute of Standards and Technology (NIST) using a new series of transportable and refillable triple-point cells.
View Article and Find Full Text PDFJ Res Natl Inst Stand Technol
December 2017
In preparation for the redefinition of the International System of Units (SI), five different electronic measurements of the Boltzmann constant have been performed using different Johnson noise thermometry (JNT) systems over the past seven years. In this paper, we describe in detail the JNT system and uncertainty components associated with the most recent National Institute of Standards and Technology (NIST) determination of the Boltzmann constant: = 1.380642 9(69) × 10 J/K, with a relative standard uncertainty of 5.
View Article and Find Full Text PDFRecent measurements using acoustic gas thermometry have determined the value of the Boltzmann constant, , with a relative uncertainty less than 1 × 10. These results have been supported by a measurement with a relative uncertainty of 1.9 × 10 made with dielectric-constant gas thermometry.
View Article and Find Full Text PDFThe last 25 years have seen tremendous progress in thermometry in the moderate temperature range (1 K to 1235 K). Various primary thermometers - based on different physics -have uncovered errors in the International Temperature Scale of 1990 and set the stage for the planned redefinition of the kelvin.
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