[Diagnostic value of the determination of total testosterone in the serum and free biologically active testosterone in the saliva in men].

The study was undertaken to provide evidence that the salivary concentration of free testosterone (FT) well correlates with the serum level of unbound testosterone in men. Recent articles demonstrate that the results obtained by the use of especially automatic systems are incorrect. Anew luminescence enzyme immunoassay has been now put into practice.

The CardioOP-Data Clas (CDC). Development and application of a thesaurus for content management and multi-user teleteaching in cardiac surgery.

Objectives: Self-directed and customized medical education programs are gaining importance in health care instruction. We prototypically implemented a repository-driven online computer system (CardioOP) for teleteaching in Heart Surgery. It supports authoring and multiple re-use of multimedia data for different user groups in different instructional applications and therefore requires a process of content management.

Incidence of malformations of the urinary tract in association with clefts of lip, alveolus, and palate.

Malformation syndromes accompanied by cleft development in the lip-alveolus-palate (LAP) region are sometimes associated with anomalies of the efferent urinary tract. In the present clinical study, 68 children with an LAP-cleft were routinely subjected to radiological examination of the efferent urinary tract. These revealed pathological alterations, in varying degrees, in 26 children.

[Frequency of urinary tract abnormalities in cleft lip-maxilla-palate patients].

Malformations of the urinary tract favour urinary tract infection; on the other hand, a urinary tract infection is often the first indication of a malformation of the urinary tract. Further signs are externally visible malformations, such as cheilognathopalatoschisis. In two years we examined 53 children with schistases urologically and found urinary tract anomalies in 39,6%.

A modified groin flap for reconstruction of oral cavity defects after tumour resection.

21 patients, suffering from carcinoma in the lower part of the oral cavity, were operated on by in-continuity resection of the mandible. The removed bone was replaced by a metal plate. The soft tissue defect was completely repaired by a modified free groin flap, transplanted with microsurgical techniques.

[Prevention of cleft palate in animal experiments. Clinical inferences (author's transl)].

The almost 100% successes with drug prophylaxis of cheilognathopalatoschisis in humans described by some authors are dubious, not only because of the dose level, but particularly because of the fact that the data do not result from controlled studies. In order to clarify the efficacy of cleft prophylaxis, we undertook animal experiments. To produce clefts, NMRI mice were treated with dexamethasone on day 13 of pregnancy.