Publications by authors named "Wessam Abdellatif"

Article Synopsis
  • A 48-week study was conducted to evaluate the safety and effectiveness of the laxative lubiprostone in patients with metabolic dysfunction-associated steatotic liver disease (MASLD), showing promising results.
  • Lubiprostone significantly reduced liver fat content compared to placebo, although it did not significantly impact fibrosis scores or serum ALT levels.
  • While the treatment was generally tolerated, with only one case of severe diarrhea in the lubiprostone group, further research is needed to confirm its efficacy for MASLD.
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Background: Hepatocellular carcinoma (HCC) is one of the most common malignancies and is the third cause of cancer-related death worldwide. Surgery is the optimal treatment for early HCC; however, the majority of cases are not suitable for curative resection at the time of diagnosis. Surgical resection difficulties may be related to size, site, number of tumors, extrahepatic involvement, and patient general condition.

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Hydatid disease is a worldwide zoonosis caused by the larval stage of the echinococcus tapeworm, that is endemic in many parts 6f the world (in Europe, Middle East, Mediterranean, South American and African countries). Hydatid disease is a relevant health problem in underdeveloped areas where veterinary control does not exist. The most frequent location of hydatid cystic lesions is the liver (up to 80% of cases), followed by the lung (about 20% of cases), and with a lower reported incidence in any other organ or tissue in the body.

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