J Environ Sci Health A Tox Hazard Subst Environ Eng
December 2024
Hexavalent Chromium (Cr(VI)) is essential in many industrial processes. However, it finds its way into water bodies, posing health problems, including lung cancer and the inhibition of DNA and RNA in biological systems. Several chemical and traditional water purification methods have been developed in the past, but most are expensive, tedious and ineffective.
View Article and Find Full Text PDFJ Environ Sci Health A Tox Hazard Subst Environ Eng
April 2024
Cellulose was isolated from recycled pulp and paper sludge and used to synthesize cellulose nanocrystals. Response surface methodology and Box-Behnken design model were used to predict, improve, and optimize the cellulose isolation process. The optimal conditions were a reaction temperature of 87.
View Article and Find Full Text PDFJ Environ Sci Health A Tox Hazard Subst Environ Eng
October 2023
Silver nanoparticles have gained worldwide attention in the scientific community due to their high antimicrobial activity. However, they tend to agglomerate and lose their shape and properties, thus capping agents necessary to protect their shapes, sizes, and properties. To enhance their antimicrobial activity, this research aimed to cap silver nanoparticles with cellulosic matrices from wheat straws.
View Article and Find Full Text PDFNarok and Bomet are agricultural counties in Kenya which depend on flowing surface waters for farming activities. Agrochemicals have frequently been used to increase agricultural produce in this region. Occasionally, appropriate pesticide utilization measures are not followed.
View Article and Find Full Text PDFDiabetes Mellitus is an endocrine disorder which causes insulin deficiency. Medicinal plants are documented to be efficacious in the management of the disease. The current research set to determine the phytochemicals present, anti-oxidant activity and investigate the potency of against α-amylase inhibition.
View Article and Find Full Text PDFAgro-wastes such as sugar cane bagasse can be explored for use in different aspects. Its applicability as a source of cellulose has attracted much interests especially in biomedical field among various applications. In the current work chemically purified cellulose (CPC) and cellulose nanocrystals (CNCs) were effectively extracted from sugarcane bagasse (SCB).
View Article and Find Full Text PDFUnlabelled: Effective use of dihydroartemisinin (DHA) is limited by poor water-solubility, poor pharmacokinetic profile and unsatisfactory clinical outcome especially in monotherapy. To reduce such limitations, we reformulated DHA into solid lipid nanoparticles (SLNs) as a nanomedicine drug delivery system. DHA-SLNs were characterized for physical parameters and evaluated for in vitro and in vivo antimalarial efficacy.
View Article and Find Full Text PDFCopper(II) and zinc(II) levels in drinkable water sources in the alluvium areas of the Lake Victoria Basin in Siaya County of Kenya were evaluated to assess the risk posed to resident communities by hydrogeological accumulation of toxic residues in the sedimentary regions of the lake basin. The levels of the metals in water were analyzed by atomic absorption spectroscopy. Metal concentrations ranged from 0.
View Article and Find Full Text PDFPrimaquine (PQ) is one of the most widely used antimalarial drugs and is the only available drug that combats the relapsing form of malaria. PQ use in higher doses is limited by severe tissue toxicity including hematological- and gastrointestinal-related side effects. Nanoformulation of drugs in an appropriate drug carrier system has been extensively studied and shown to have the potential to improve bioavailability, thereby enhancing activity, reducing dose frequency, and subsequently reducing toxicity.
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