Publications by authors named "Wesley N Omwoyo"

Hexavalent Chromium (Cr(VI)) is essential in many industrial processes. However, it finds its way into water bodies, posing health problems, including lung cancer and the inhibition of DNA and RNA in biological systems. Several chemical and traditional water purification methods have been developed in the past, but most are expensive, tedious and ineffective.

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Cellulose was isolated from recycled pulp and paper sludge and used to synthesize cellulose nanocrystals. Response surface methodology and Box-Behnken design model were used to predict, improve, and optimize the cellulose isolation process. The optimal conditions were a reaction temperature of 87.

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Unlabelled: Effective use of dihydroartemisinin (DHA) is limited by poor water-solubility, poor pharmacokinetic profile and unsatisfactory clinical outcome especially in monotherapy. To reduce such limitations, we reformulated DHA into solid lipid nanoparticles (SLNs) as a nanomedicine drug delivery system. DHA-SLNs were characterized for physical parameters and evaluated for in vitro and in vivo antimalarial efficacy.

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Copper(II) and zinc(II) levels in drinkable water sources in the alluvium areas of the Lake Victoria Basin in Siaya County of Kenya were evaluated to assess the risk posed to resident communities by hydrogeological accumulation of toxic residues in the sedimentary regions of the lake basin. The levels of the metals in water were analyzed by atomic absorption spectroscopy. Metal concentrations ranged from 0.

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Primaquine (PQ) is one of the most widely used antimalarial drugs and is the only available drug that combats the relapsing form of malaria. PQ use in higher doses is limited by severe tissue toxicity including hematological- and gastrointestinal-related side effects. Nanoformulation of drugs in an appropriate drug carrier system has been extensively studied and shown to have the potential to improve bioavailability, thereby enhancing activity, reducing dose frequency, and subsequently reducing toxicity.

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