Assessment of possible immunotoxicity of the antipsychotic drug clozapine.

Objectives: The immunomodulatory effects of clozapine (CLZ), antipsychotic drug, were investigated in vivo using female Balb/c mice. The main aim of this study was to evaluate the immunomodulatory effects of CLZ, antipsychotic drug, following daily intraperitoneal injection to female Balb/c mice over a period of 21 days.

Methods: Mice were divided into five groups, eight animals per group.