Publications by authors named "Werner Lukas Pabst"
Pediatr Nephrol
July 2013
Article Synopsis
- Atypical haemolytic uremic syndrome (aHUS) poses a high risk of recurrence and graft loss in kidney transplants, especially when caused by mutations in complement factor I (CFI) and membrane cofactor protein (MCP).
- A 9-year-old boy with combined mutations in CFI and MCP was successfully transplanted at age 5, receiving fresh frozen plasma during and after the procedure, which was halted after three years.
- After 5 years of follow-up, the boy showed no signs of recurrent aHUS, suggesting that these genetic mutations may lead to a better post-transplant outcome and lower aHUS recurrence risk.
