The purpose of this study was to compare microbial leakage of Enterococcus faecalis after post space preparation in teeth filled in vivo with RealSeal (SybronEndo, Orange, CA) versus gutta percha. Twenty-six premolars in which extraction was indicated for orthodontic reasons were endodontically treated before extraction to simulate normal clinical conditions. Ten of these bicuspids were obturated following the RealSeal protocol; the other 10 were filled with gutta percha and Grossman-based formula cement.
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