[Magnetic resonance imaging in prenatal diagnosis].

Author discusses methods of magnetic resonance imaging and in status in the prenatal diagnosis as well as the impact of examination on the management plan for treatment of fetus and newborn.

Prenatal diagnosis of a brain tumour--an example of diagnostic and therapeutical algorithm.

The authors describe their cooperation in the diagnosis and treatment of a newborn with malignant brain tumour (rare case of carcinoma of the choroid plexus) recognised by means of prenatal sonography and magnetic resonance. The case history is an example of modern algorithm of diagnostic and therapeutic procedures in perinatal medicine and the necessary multicentre collaboration.

[Value of diagnostic imaging for assessment of unsuccessful treatment of children with neoplastic diseases. Introductory comments based on personal examinations].

Diagnostic imaging has determined clinical application depending on kind of pathology and anatomical localisation. This is a precise and fine instrument for monitoring effects of treatment in childhood malignant tumours. Authors demonstrate examples of cases in which diagnostic imaging was the only method which revealed a relapse in situ, progression during chemotherapy or clinically unsuspected dissemination of tumours after many years.

Percutaneous transsplenic embolization of esophageal varices in a 5-year-old child.

A five-year-old girl with portal vein thrombosis and severe gastrointestinal hemorrhage recurring after repeated endoscopic sclerotherapy was successfully embolized via an ultrasonically guided transsplenic catheterization of the splenic vein.

Clinical features in a case with ring chromosome 13.

A 30-month-old boy with severe psychomotor retardation and numerous developmental anomalies, such as small trigonocephalic head, craniofacial anomalies, malformations of fingers with hypoplastic thumbs, anomalies of urogenital organs and imperforate anus, is presented. Cytogenetic studies of peripheral blood lymphocytes with differential staining of chromosomes revealed 46,XY,r13 karyotype. The correlation between clinical features and the observed chromosome aberration is discussed.

A new case of partial trisomy of 17 long arm. Densitometric analysis of aberrations.

Partial trisomy of the long arm of the chromosome 17 was found in a male infant with severe psychomotor retardation and numerous developmental anomalies. Differential staining with GTG, QFQ and CBG methods revealed an excess of genetic material on the short arm of chromosome 14, which was preliminarily identified as the distal part of chromosome 17q. Using an automatic picture analyser, chromosome break points were found in the 17q12 and 14p12 bands.

Instestinal obstruction as a late complication in rotentgen therapy of Wilms' tumor.

A case of intestinal obstruction, as a result of radiation injury of the colon, is reported. This child was treated by roentgen therapy in the infant period because of a Wilms' tumour of the left kidney.

[Angiocardiography in the diagnosis of congenital bulboventricular heart defects. Anatomopathological and angiocardiographic correlations].

Current surgical methods enable radical treatment of the most bulboventricular malformations (syn. conotruncal malformations, transposition complex). The defects, which were until now the field of embryologist and pathologist, require accurate and precise clinical diagnosis of the anomaly.

[Vascular complications of angiography in childhood (author's transl)].

Evaluation of 500 arteriograms in children over a period of three years revealed a complication rate of 7.4% (37 cases). In these, thrombosis occurred which had to be treated conservatively.

Angiographic evaluation of conjoined twins.

Two sets of conjoined twins were studied by angiocardiography and cerebral angiography. Conjoined heart was demonstrated in the thoracopagus twins and surgical separation was impossible. Cerebral angiography disclosed the separate circulations in craniopagus twins and surgical separation was performed.