Publications by authors named "Wenzhuo Du"
Article Synopsis
- Spaghetti knotting technology shows promise in improving LESS surgery by enhancing the operator's visual field and suturing accuracy compared to traditional knotting methods.
- A study involving 40 junior residents found that those trained with spaghetti knotting technology completed tasks faster, used longer threads, and maintained better tissue integrity than those using conventional methods.
- Overall, while the new technique reduced workload and improved performance in specific areas, both training methods had similar outcomes in needle insertion accuracy, knotting stability, and tissue tightness.
Article Synopsis
- - The study compares hidden blood loss (HBL) between laparoendoscopic single-site myomectomy (LESS-M) and conventional laparoscopic myomectomy (CLM) for treating uterine leiomyoma, finding that HBL was significantly higher in the LESS-M group.
- - A total of 270 patients (114 for LESS-M and 156 for CLM) were analyzed, with methods including clinical data collection and statistical analysis using the Nadler and Gross formula.
- - The findings indicate that HBL represents a considerable portion of total blood loss (TBL), highlighting the need for careful monitoring of blood changes during and after surgeries to aid in patient recovery.
Autophagy has emerged as an important process of cell metabolism. With continuous in-depth research on autophagy, TFEB has been a key transcription factor regulating autophagy levels in recent years. Studies have established that TFEB regulates autophagy and apoptosis in various diseases.
View Article and Find Full Text PDFObjective: To investigate the influence and significance of cGAS-STING signaling pathway and autophagy on the occurrence and development of preeclampsia.
Design: A case-control experimental study, in vitro cell culture study, and in vivo animal research.
Methods: Human placenta tissue was collected and the differences in HE staining were observed.
The cGAS-STING pathway promotes endometriosis by up-regulating autophagy.
Int Immunopharmacol
April 2023
Objective: To investigate the roles of the cGAS-STING signal pathway and autophagy in the disease progression of endometriosis and to explore the regulatory mechanism of the cGAS-STING signal pathway on autophagy.
Design: A case-control experimental study, in vitro primary cell culture study, and in vivo animal research.
Main Outcome Measures: Immunohistochemistry, RT-PCR and Western Blot were used to detect cGAS-STING signal pathway and autophagy expression differences in human and rat models.