Publications by authors named "Wenzhao Guan"

Article Synopsis
  • Graphite carbon nitride (CN) has potential as a cancer treatment by converting hydroxyl radicals (HO) into harmful hydroxyl radicals (•OH) using light, but its effectiveness is limited by insufficient HO and harmful accumulation of •OH.
  • The research introduces Fe/N-CN, which combines nitrogen vacancies and ferric ions to enhance •OH production and improve electron and hole transfer, facilitating more effective cancer cell targeting.
  • This novel system not only prevents the negative buildup of •OH, making it a promising photosensitizer for photodynamic therapy, but also demonstrates a new method for optimizing semiconductor photosensitizers to improve cancer treatment outcomes.
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Background: Studies have shown that microRNA-191 (miR-191) is involved in the development and progression of a variety of tumors. However, the function and mechanism of miR-191 in oral squamous cell carcinoma (OSCC) have not been clarified.

Methods: The expression level of miR-191 in tumor tissues of patients with primary OSCC and OSCC cell lines were detected using real-time quantitative polymerase chain reaction (RT-qPCR) and western blot.

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Background: Accurate diagnostic techniques for patients with primary Sjögren's syndrome (pSS) are needed. This study aimed to investigate new biomarkers related to fecal and plasma metabolism from pSS patients.

Methods: The feces and plasma of 21 pSS patients and 18 controls admitted to the Second Hospital of Shanxi Medical University were collected for analysis.

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