Inflammation, a central process in numerous diseases, plays a crucial role in hepatic disorders, arthritis, cardiac conditions, and neurodegenerative ailments. Given the lack of effective anti-inflammatory drugs, it is imperative to assess inflammation severity and explore novel therapeutics. Selenocysteine (Sec), a key mediator of selenium's biological function, is closely involved in anti-inflammatory responses.
View Article and Find Full Text PDFCurr Issues Mol Biol
December 2024
The Y-box binding protein 1 (YBX1) is a multifunctional protein with a wide range of roles in cell biology. It plays a crucial role in immune modulation, senescence, and disease progression. This review presents a comprehensive analysis of the specific functions and mechanisms of YBX1 in these areas.
View Article and Find Full Text PDFAgrobacterium-mediated transient expression is a flexible and efficient technique for introducing genes into plants, allowing for rapid and temporary gene expression. Agroinfiltration of Arabidopsis seedlings is a newly developed Agrobacterium-based transient expression system. The expression of target genes and the localization of relevant proteins can be observed within 3 days using this method.
View Article and Find Full Text PDFSupramolecular engineering is exceptionally appealing in the design of functional materials, and J-aggregates resulting from noncovalent interactions offer intriguing features. However, building J-aggregation platforms remains a significant challenge. Herein, we report 3,5-dithienyl Aza-BODIPYs with a donor-acceptor-donor (D-A-D) architecture as the first charge transfer (CT)-coupled J-aggregation BODIPY-type platform.
View Article and Find Full Text PDFThe contact state of a seamless internal threaded copper tube and an aluminium foil fin not only affects the heat transfer efficiency of a tube-fin heat exchanger but also seriously affects its service life. In this study, hydraulic expansion technology was used to connect the copper tube with an internal thread with a 7 mm diameter to the fin of the heat exchanger. The influence of the expansion pressure and pressure holding time on the contact state was analysed through experiments and finite element simulation, and the variation law of the two on the contact state was obtained.
View Article and Find Full Text PDFThe construction of novel organoboron complexes with facile synthesis and unique advantages for biological imaging remains a challenge and thus has garnered considerable attention. Herein, we developed a new molecular platform, boron indolin-3-one-pyrrol (BOIN3OPY) via a two-step sequential reaction. The molecular core is robust enough to allow for post-functionalization to produce versatile dyes.
View Article and Find Full Text PDFIncreased evidence has shown that hydrogen sulfide (HS), a novel gasotransmitter, could enhance drought resistance in plants by inducing stomatal closure, with concurrent enhancement of photosynthetic efficiency, but little is known about the mechanism behind this contradictory phenomenon. This study examined the regulating mechanism of HS in response to drought stress from stomatal and non-stomatal factors in Chinese cabbage. The results showed that exogenous HS could increase the accumulation of photosynthetic pigments and alleviate the damage caused by drought stress.
View Article and Find Full Text PDFCoastal macroalgae may be subjected to global and local environmental stressors, such as ocean acidification and heavy-metal pollution. We investigated the growth, photosynthetic characteristics, and biochemical compositions of juvenile sporophytes of cultivated at two pCO levels (400 and 1000 ppmv) and four copper concentrations (natural seawater, control; 0.2 μM, low level; 0.
View Article and Find Full Text PDFEnviron Sci Pollut Res Int
March 2023
Sulfur dioxide (SO) is a toxic pollutant and its fixation is a high cost but imperative task for sulfide metallurgy industry. Although being a mature technology for on-line fixation of SO by limestone injection in coal-fired boilers, its application is rarely investigated in the sulfide metallurgy plant. Extending this technology to the metallurgy industry is highly plausible, but with the feasibility and practicability waiting to be uncovered.
View Article and Find Full Text PDFThe combined effect of elevated pCO (Partial Pressure of Carbon Dioxide) and decreased salinity, which is mainly caused by freshwater input, on the growth and physiological traits of algae has been poorly assessed. In order to investigate their individual and interactive effects on the development of commercially farmed algae, the juvenile sporophytes of were cultivated under different levels of salinity (30, 25 and 20 psu) and pCO (400 and 1000 µatm). Individually, decreased salinity significantly reduced the growth rate and pigments of , indicating that the alga was low-salinity stressed.
View Article and Find Full Text PDFThe clinching process is widely used in joining lightweight sheet metal. We proposed a novel rotated clinching process (RCP), which is characterized by a flat bottom die structure and twin rotating punches. The aim of this study was to evaluate the strength of RCP joints.
View Article and Find Full Text PDFFour new indole--mannopyranoside alkaloids, neopetrosins A-D (-), together with one new diamine alkaloid, haliclorensin D (), were isolated from the marine sponge collected off Xisha Island in the South China Sea. Their structures and absolute configurations were determined by spectroscopic analysis, single-crystal X-ray diffraction, calculated electronic circular dichroism (ECD), and DP4+ probability analyses. Compounds , , and exhibited in vivo hepatoprotective activity in a zebrafish model at a concentration of 20 μM.
View Article and Find Full Text PDFBeilstein J Org Chem
April 2022
Four new polyhydroxylated steroids lobophysterols E-H (-), together with three known compounds (-), were isolated from the soft coral collected at Xisha Island, China. The structures of the new compounds were elucidated by extensive spectroscopic analysis and comparison with NMR data of structurally related compounds reported in the literature. The absolute configuration of - was determined by X-ray diffraction.
View Article and Find Full Text PDFThe kidney is a vital organ and susceptible to various diseases. Photoacoustic (PA) imaging provides a powerful technique for studying kidney dysfunction, for which many smart photoacoustic imaging agents have been developed. But the complete clearance of the introduced contrast agents after imaging remains to be challenging, leading to long-term toxicity concerns.
View Article and Find Full Text PDFSpectrochim Acta A Mol Biomol Spectrosc
September 2021
Two novel single-armed nitrogen-heterocyclic chemosensors with basically similar structures, PDNS and PZNS, were synthesized to specifically identify Al in DMS:HO (1:1 v/v) solution by fluorescence emission spectroscopy, and the colour of PDNS and PZNS changed from yellow to colorless when Al was added under daylight. This is the first time that nitrogen-heterocyclic is introduced into salamo-based chemical sensor. At excitation wavelengths of 361 and 365 nm, solutions of PDNS and PZNS changed to intense green-blue fluorescence.
View Article and Find Full Text PDFBackground: Despite significant limitations of growth medium reuse, a large amount of organic substrate is reused in soilless cultivation of horticultural crops in China. Arbuscular mycorrhizal fungi (AMF) can promote nutrient absorption and improve plant tolerance to biotic and abiotic stresses. However, the mechanisms governing the effects of AMF on crop growth in organic continuous cropping substrates have not been elucidated.
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