Overview of evidence-based research on acupuncture for stroke treatment using magnetic resonance imaging technology.

Background: Stroke is a neurological condition characterized by high rates of disability and mortality. Magnetic resonance imaging (MRI) is widely used to examine the mechanisms of acupuncture in stroke treatment.

Purpose: This review provides neuroimaging evidence for the efficacy of acupuncture in treating stroke using MRI.

Long organic persistent luminescence triggered by photo-induced charge-separation for water-resistant information encryption.

The long persistent luminescence (LPL) phenomenon in the water environment presents us with a broad blueprint to struggle for a new generation of optical materials. However, the realization of water-resistant LPL remains a formidable challenge due to severe quenching of triplet excitons inflowing media. Here, an electron donor-acceptor system is designed based on a BO host and carbon dot (CD) guest, which exhibits deep-blue LPL with a lasting time of about 21 s to the naked eye.

Exploring the bioactive ingredients of three traditional Chinese medicine formulas against age-related hearing loss through network pharmacology and experimental validation.

Traditional Chinese medicine (TCM) formulas, including the Er-Long-Zuo-Ci pill, Tong-Qiao-Er-Long pill, and Er-Long pill, have long been utilized in China for managing age-related hearing loss (ARHL). However, the specific bioactive compounds, pharmacological targets, and underlying mechanisms remain elusive. This study aims to find the shared bioactive ingredients among these three formulas, uncover the molecular pathways they regulate, and identify potential therapeutic targets for ARHL.

Linking reproductive tract microbiota to premature ovarian insufficiency: Pathophysiological mechanisms and therapies.

Over the past decade, research on the human microbiota has become a hot topic. Among them, the female reproductive tract (FRT) also has a specific microbiota that maintains the body's health and dynamic balance, especially in the reproductive aspect. When the FRT ecosystem is dysregulated, changes in immune and metabolic signals can lead to pathological and physiological changes such as chronic inflammation, epithelial barrier disruption, changes in cell proliferation and apoptosis, and dysregulation of angiogenesis and metabolism, thereby causing disruption of the female endocrine system.

Metastable Supramolecular Assembly of Simple Monomers Enabled by Confinement: Towards Aqueous Phase Room Temperature Phosphorescence.

The application of supramolecular assembly (SA) with room temperature phosphorescence (RTP) in aqueous phase has the potential to revolutionize numerous fields. However, using simple molecules with crystalline RTP to construct SA with aqueous phase RTP is hardly possible from the standpoint of forces. The reason lies in that the transition from crystal to SA involves a structure transformation from highly stable to more dynamic state, leading to increased non-radiative deactivation pathways and silent RTP signal.

The mediating effect of self-efficacy on family functioning and psychological resilience in prostate cancer patients.

Aims: Prostate cancer patients face impaired body image and psychological distress during the diagnosis and treatment of the disease, which leads to changes in mood, cognition and behavior. Psychological resilience has been shown to buffer shocks and stresses from the disease. Therefore, this study investigates the relationship between family functioning and psychological resilience in prostate cancer patients and the mediating role of self-efficacy between family functioning and psychological resilience to provide a relevant theoretical basis for improving patients' psychological status by providing relevant theoretical basis.

Dynamic gut microbiome-metabolome in cationic bovine serum albumin induced experimental immune-complex glomerulonephritis and effect of losartan and mycophenolate mofetil on microbiota modulation.

Dynamic changes in gut dysbiosis and metabolomic dysregulation are associated with immune-complex glomerulonephritis (ICGN). However, an in-depth study on this topic is currently lacking. Herein, we report an ICGN model to address this gap.

Potential Effects of NO-Induced Hypoxia-Inducible Factor-1α on Yak Meat Tenderness during Post-Mortem Aging.

The objective of this study was to investigate the mechanism underlying nitric oxide (NO)-induced hypoxia-inducible factor-1α (HIF-1α) and its impact on yak muscle tenderness during post-mortem aging. The Longissimus thoracis et lumborum (LTL) muscle of yak were incubated at 4 °C for 0, 3, 6, 9, 12, 24, and 72 h after treatment with 0.9% saline, NO activator, or a combination of the NO activator and an HIF-1α inhibitor.

The effect of nutritional biochemical indexes on the hospitalization outcome of COVID-19.

Aims to investigate the relationship between nutritional biochemical indexes and hospitalization outcomes of COVID-19 patients, 132 continuous patients with COVID-19 from December 2022 to January 2023 in Lishui hospital were retrospectively analyzed, and the nutritional biochemical indexes in peripheral blood, such as total protein, albumin, calcium, phosphorus, and magnesium, were detected. Meanwhile, the levels of several cytokines and PBMC subtypes (CD4, CD3, CD8, NK and B cells) were detected too. The Spearman correlation analysis, one-way ANOVA and multivariate logit regression were conducted.

Emerging trends and research priorities in premature ovarian insufficiency genes: a bibliometric and visualization study.

Purpose: To illustrate the results achieved by genes in premature ovarian insufficiency (POI) and collaborations in the field, and to explore key themes and future directions.

Methods: Articles and reviews related to POI genes published between 1990 and 2022 were retrieved from the Web of Science core collection (WoSCC) for the total bibliometric analysis. Tools were analyzed for publication, country, institution, journal, authors, reference, keywords, subject categories, funding agencies, and research hotspots using a bibliometric online analysis platform, Bibliographic Co-occurrence Matrix Builder (BICOMB), CiteSpace V, and VOSviewer.

Altered Intestinal Microbial Flora and Metabolism in Patients with Idiopathic Membranous Nephropathy.

Introduction: Dysbiosis of the intestinal microbiome and related metabolites have been observed in chronic kidney disease, yet their roles in idiopathic membranous nephropathy (IMN) are poorly understood.

Methods: In this study, we describe the variation of intestinal bacteria and fecal metabolites in patients with IMN in Chinese population. Stool samples were collected from 41 IMN patients at the beginning of diagnosis confirmation and 41 gender- and age-matched healthy control (HC).

Acupuncture and moxibustion for diminished ovarian reserve: A scoping review.

Objective: Diminished ovarian reserve (DOR) refers to the decreased number and quality of oocytes in the ovary. Acupuncture and moxibustion has a certain effect on DOR; however, the number of studies and reports of research evidence are limited. This study aimed to conduct a scoping review of the clinical research status of acupuncture and moxibustion for treating patients with DOR.

Dynamic Control over Hierarchically Dendritic Architectures of Simple Heterogenous Monomers by Living Supramolecular Assembly.

The successful preparation of supramolecular block copolymers (SBCPs) by living supramolecular assembly technology requires two kinetic systems in which both the seed (nucleus) and heterogenous monomer providers are in non-equilibrium. However, employing simple monomers to construct the SBCPs via this technology is almost impossible because the low spontaneous nucleation barrier of simple molecules prevents the formation of kinetic states. Here, with the help of confinement from layered double hydroxide (LDH), various simple monomers successfully form living supramolecular co-assemblies (LSCA).

Biased Symmetry Breaking in the Formation of Intercalated Layered Double Hydroxides: toward Control of Homochiral Supramolecular Assembly.

Homochiral supramolecular assembly (HSA) based on achiral molecules has provided important clues to understand the origin of biological homochirality from the aspect of symmetry breaking. However, planar achiral molecules still face the challenge of forming HSA due to the lack of driving force for twisted stacking, which is a prerequisite for homochirality. Here, with the benefit of the formation of 2D intercalated layered double hydroxide (LDH, host-guest nanomaterials) in vortex motion, planar achiral guest molecules can form the chiral units with spatially asymmetrical structure in the confinement space of LDH.

7-hydroxycoumarin-β-D-glucuronide protects against cisplatin-induced acute kidney injury via inhibiting p38 MAPK-mediated apoptosis in mice.

Aims: Cisplatin is a widely-used drug in the clinical treatment of tumors, but kidney nephrotoxicity is one of the reasons that limits its widespread use. We previously found that 7-hydroxycoumarin-β-D-glucuronide (7-HCG) was one of metabolites of skimmin and highly enriched in the kidneys and maintained a high blood concentration in skimmin-treated rats. Therefore, we investigated whether 7-HCG has a protective effect on cisplatin-induced acute kidney injury.

Time-dependent Phosphorescence Color of Carbon Dots in Binary Salt Matrices through Activations by Structural Confinement and Defects for Dynamic Information Encryption.

The emergence of time-dependent phosphorescence color (TDPC) materials has taken information encryption to high-security levels. However, due to the only path of exciton transfer, it is almost impossible to obtain TDPC for chromophores with a single emission center. Theoretically, in inorganic-organic composites, the exciton transfer of organic chromophores depends on the inorganic structure.

Biomimetic mineralization of nacre-inspired multiple crosslinked PVA/CaAlg/SiO membrane with simultaneously enhanced mechanical and separation properties.

Inspired by the natural nacre structure, we propose a new strategy to fabricate mineralized, multiple crosslinked hydrogel membranes with the "rigid silica in soft polymer" nacre-like structure. In-situ SiO nanoparticles (NPs) and polyvinyl alcohol/sodium alginate (PVA/NaAlg) are used to simulate the rigid "bricks" and soft "mortar" compositions of nacre, respectively. The nacre-like mineralized (PVA/CaAlg/SiO) membrane showed a higher tensile strength of 4.

Chiral Hierarchical Architecture Induced by Confinement-Assisted Living Supramolecular Polymerization of Simple Achiral Molecules.

Chiral supramolecular assembly (CSA) based on achiral molecules has provided important clues to understand the origin of biological chirality. However, a simple achiral monomer faces the challenge of chiral stacking with the absence of a chiral resource. The difficulty is that simple achiral monomer lacks steric repulsion to provide asymmetry during hierarchical assembly, which is a prerequisite for chiral stacking with an angle.

Construction of a Highly Anisotropic Supramolecular Assembly Assisted by a Dimensional Confinement Space: Toward Perovskite Solar Cells.

Solution-processed polycrystalline perovskites (PVKs) have aroused tremendous interest in the optoelectronic device field. However, the inherent high-density defects in the polycrystalline hindered achieving efficient and stable large-area PVK solar cells (PSCs). Although organic molecules are already employed to passivate PVK defects, they are insulating by nature, limiting the carrier transport.

Photoluminescence Mechanism of Carbon Dots: Triggering Multiple Color Emissions through Controlling the Degree of Protonation.

Carbon dots (CDs) have excellent optical properties, low toxicity and easy preparation, which have led to them being widely used in biomedicine, sensing and optical devices. However, although great progress has been made in the preparation of CDs, the detailed exploration of their photoluminescence (PL) mechanism is still under debate due to their complex structures and surface functionalities. Here, we proposed a single change in the pH of the synthesis condition, which had no effect on the CDs intrinsic core states and avoided the mutual influence of multiple PL origins.

Transcriptomic Profiling of Electroacupuncture Regulating the Molecular Network in Hippocampus of Rats with Cerebral Ischemia-Reperfusion Injury.

Objective: To explore the mechanism of electroacupuncture stimulation of the hand-taiyin meridian in regulating the molecular network of rats with cerebral ischemia-reperfusion injury based on transcriptomics.

Methods: Male SD rats were randomly divided into sham operation group, model group, and electroacupuncture (EA) group. Middle cerebral artery embolization/reperfusion injury (MCAO/R) was used to establish the model group and EA group.

The Insolubility Problem of Organic Hole-Transport Materials Solved by Solvothermal Technology: Toward Solution-Processable Perovskite Solar Cells.

Generally, the high efficiency of solution-processable perovskite solar cells (PSCs) comes at the expense of using expensive organic matters as a hole-transport material (HTM). Although intense efforts have tried to use commercially available and low-cost macrocyclic molecules as HTM candidates, they still face two enormous challenges: poor solubility and inherent instability. Here, solvothermal treatment for old and insoluble HTMs (phthalocyanine (Pc) and its derivatives) has been proposed, which is unusual due to the occurrence of solubilization for insoluble precursors induced by the carbonization of the dissolved part.

[Analysis on acupoint selection rules for impotence treated with acupuncture and moxibustion in ancient based on data mining technology].

Based on the data mining technology, the rules of acupoint selection and prescription were analyzed for impotence treated with acupuncture and moxibustion in ancient recorded in . By taking "" and "" as the searching terms, the database of (the 5th edition) were retrieved and the relevant information of impotence, such as prescription provision, acupoints and use frequency were extracted. Using the software, e.