Publications by authors named "Wenyan Ji"
Objectives: Restless legs syndrome (RLS), a common, treatable, sensorimotor disorder of nighttime uncomfortable leg sensations that interfere with sleep, may prompt nighttime agitation in persons with dementia.
Design: This randomized trial was double-blind and placebo-controlled. Participants received a Food and Drug Administration-approved drug for RLS, gabapentin enacarbil (GEn) (Horizant) or placebo.
Zwitterionic membranes demonstrate excellent antifouling property in water purification. The covalent organic frameworks (COFs), due to the ordered channels and abundant organic functional groups, have distinct superiority in constructing zwitterionic surfaces.Here, the zwitterionic COF membrane is prepared with precise framework structures and uniform charge distribution.
View Article and Find Full Text PDFPrecious metals are valuable materials for the chemical industry, but they are scarce and pose a risk of supply disruption. Recycling precious metals from waste is a promising strategy, here we tactfully utilize light irradiation as an environmental-friendly and energy-saving adjunctive strategy to promote the reduction of precious metal ions, thereby improving the adsorption capacity and kinetics. A newly light-sensitive covalent organic framework (PP-COF) was synthesized to illustrate the effectiveness and feasibility of this light auxiliary strategy.
View Article and Find Full Text PDFArticle Synopsis
- * This new approach effectively controls viCOF layer growth in a two-dimensional plane, resulting in higher quality structures with improved crystallinity and porosity achieved in a shorter reaction time.
- * The research highlights a unique growth pattern discovered through this method, which facilitates orderly monomer assembly and allows for gram-scale production of 2D viCOFs, offering a promising direction for future advancements in the field.
Article Synopsis
- - The study focuses on developing a fluorine-containing 2D polymer film (F-2DP) to improve charge transport in organic electronics, addressing challenges in synthesis and material availability.
- - A new polar molecule is created and incorporated into the F-2DP, enhancing its crystallinity and enabling efficient charge transport, resulting in a device that exhibits multilevel memory behavior.
- - The device demonstrates ternary memory behavior with distinct resistance states and accuracy in neuromorphic computing, indicating strong potential for future technology applications in a post-Moore era.
Purpose: Oropharyngeal squamous cell cancers (OPSCCs) are traditionally managed with surgery and, if indicated, adjuvant radiation therapy (RT) with or without chemotherapy. NCCN recommends keeping the time from surgery to the start of RT (TSRT) within 6 weeks to avoid possibly compromising patient outcomes. HPV+ OPSCCs behave more favorably than HPV- OPSCCs.
View Article and Find Full Text PDF[Comparative metabolomics analysis of metabolic pathways in the high-yielding mutant strain of avilamycin].
Sheng Wu Gong Cheng Xue Bao
June 2024
Avilamycin (AVI) is an oligosaccharide antibiotic that has strong inhibitory effect on Gram-positive bacteria. It is widely used in livestock and poultry farming. However, the use of traditional breeding techniques and immature fermentation process have become the key factors limiting its commercialization.
View Article and Find Full Text PDFObjective: To assess differences in longitudinal profiles for 30-day risk-adjusted readmission rates in skilled nursing facilities (SNFs) associated with Penn Medicine's Lancaster General Hospital (LGH) that implemented an interventional analytics (IA) platform vs other LGH facilities lacking IA vs other SNFs in Pennsylvania vs facilities in all other states.
Study Design: Retrospective longitudinal analysis of CMS readmissions data from 2017 through 2022, and cross-sectional analysis using CMS quality metrics data.
Methods: CMS SNF quality performance data were aggregated and compared with risk-adjusted readmissions by facility and time period.
Background: Obstructive sleep apnea (OSA) has been shown to be an important risk factor for cardiovascular disease (CVD), and intermittent hypoxia is an important pathogenetic factor for it. In the clinic, it was found that most CVD patients combined with OSA were also combined with solitary pulmonary nodules (SPN) or thyroid nodules (TN). Are these disorders related to intermittent hypoxia? One study showed that intermittent hypoxia is a pathogenic factor for lung cancer in mice, but there have been no clinical reports.
View Article and Find Full Text PDFBackground: In patients with severe traumatic brain injury (TBI), clinicians must balance preventing venous thromboembolism (VTE) with the risk of intracranial hemorrhagic expansion (ICHE). We hypothesized that low molecular weight heparin (LMWH) would not increase risk of ICHE or VTE as compared to unfractionated heparin (UH) in patients with severe TBI.
Methods: Patients ≥ 18 years of age with isolated severe TBI (AIS ≥ 3), admitted to 24 level I and II trauma centers between January 1, 2014 to December 31, 2020 and who received subcutaneous UH and LMWH injections for chemical venous thromboembolism prophylaxis (VTEP) were included.
Introduction: Invisible ink tattoos (IITs) avoid cosmetic permanence of visible ink tattoos (VITs) while serving as more reliable landmarks for radiation setup than tattooless setups. This trial evaluated patient-reported preference and feasibility of IIT implementation.
Methods And Materials: In an IRB-approved, single institution, prospective trial, patients receiving proton therapy underwent IIT-based treatment setup.
Background: The COVID-19 pandemic has experienced various phases including outbreaks, a global health crisis, and eventual de-escalation from a public health emergency of international concern, significantly affecting the delivery and utilization of healthcare services. This study aimed to evaluate the impact of the COVID-19 pandemic on the coverage rate of routine immunization in children under varying prevalence conditions.
Methods: We conducted a retrospective, population-based cohort study in Beijing, China, utilizing stratified random sampling by birthdate to obtain a sample of 29,811 participants.
Objective: To examine family medicine (FM) and obstetrician-gynecologist (OB/GYN) residents' experiences with CenteringPregnancy (CP) group prenatal care (GPNC) as a correlate to perceived likelihood of implementing CP in future practice, as well as knowledge, level of support, and perceived barriers to implementation.
Methods: We conducted a repeated cross-sectional study annually from 2017 to 2019 with FM and OB/GYN residents from residency programs in the United States licensed to operate CP. We applied adjusted logistic regression models to identify predictors of intentions to engage with CP in future practice.
Background: Cholangiocarcinomas (CCAs) are rare and aggressive malignant tumors of the biliary tract. Serotonin (5HT) has tumor-promoting effects in CCA while inhibition of 5HT synthesis can decrease tumor growth.
Methods: In this retrospective study, we evaluated the expression of 5HT and tryptophane hydroxylase-1 (TPH-1) in tumor specimens from patients treated with cisplatin plus gemcitabine (CisGem).
Article Synopsis
- The healthcare system is focusing on providing better care, and one way to do that is through a program called bundled care payment model (BCPM), which helps patients get quality treatment.
- They created a special program for patients who travel more than 2 hours to receive care at a bariatric center, called the destination bariatric program.
- The study looked at 296 patients and found that even though destination patients had more diabetes, both groups had similar health outcomes after surgery, meaning both types of patients did equally well.
Article Synopsis
- The performance of covalent organic frameworks (COFs) is influenced by the design of their pore structures and functionalization.
- Researchers developed a COF with unique hetero-environmental pores using a specific asymmetrical dialdehyde monomer, which enhances its properties for loading a mix of antibiotics.
- This dual-antibiotic approach not only broadens the antibacterial effectiveness but also helps to minimize drug resistance, showcasing the potential of tailored COF designs for practical applications.
Background: The routine immunization program for children is a primary strategy and a core part of vaccination. Achieving and maintaining high level of vaccination coverage are important to reduce morbidity and mortality caused by vaccine-preventable diseases. In Beijing, annual coverage surveys have been conducted since 2005.
View Article and Find Full Text PDFBackground: Multidisciplinary teams (MDT) aid the diagnosis and management of patients with inflammatory bowel disease (IBD) and improve patient outcomes. The direct impact of a gastrointestinal expert pathologist on MDT care of IBD patients is unknown.
Methods: A retrospective chart review was conducted evaluating all cases (N = 289) discussed at the IBD MDT conference at Carilion Roanoke Memorial Hospital from June 1, 2013, through December 31, 2019.
Objectives: Although radiofrequency catheter ablation (RFCA) has become an important treatment strategy for paroxysmal or persistent atrial fibrillation (AF), AF recurrence after RFCA remains an important issue that plagues clinicians and patients. This study aimed to investigate the association of left atrial (LA) and left atrial appendage (LAA) mechanics with AF recurrence after RFCA and to compare their prognostic values in patients with AF undergoing RFCA.
Methods: A total of 160 patients with non-valvular AF who underwent RFCA for the first time were included in this study.
Constructing a powerful photocatalytic system that can achieve the carbon dioxide (CO ) reduction half-reaction and the water (H O) oxidation half-reaction simultaneously is a very challenging but meaningful task. Herein, a porous material with a crystalline topological network, named viCOF-bpy-Re, was rationally synthesized by incorporating rhenium complexes as reductive sites and triazine ring structures as oxidative sites via robust -C=C- bond linkages. The charge-separation ability of viCOF-bpy-Re is promoted by low polarized π-bridges between rhenium complexes and triazine ring units, and the efficient charge-separation enables the photogenerated electron-hole pairs, followed by an intramolecular charge-transfer process, to form photogenerated electrons involved in CO reduction and photogenerated holes that participate in H O oxidation simultaneously.
View Article and Find Full Text PDFBackground: Almost 60% of adults with amnestic mild cognitive impairment (aMCI) have obstructive sleep apnea (OSA). Treatment with continuous positive airway pressure (CPAP) may delay cognitive decline, but CPAP adherence is often suboptimal. In this study, we report predictors of CPAP adherence in older adults with aMCI who have increased odds of progressing to dementia, particularly due to Alzheimer's disease.
View Article and Find Full Text PDFArticle Synopsis
- Class IV dental diode lasers were studied as a nonsurgical treatment for periodontal pockets in dogs, aiming to reduce pocket depth in a specialty veterinary dental practice.
- A total of 12 dogs with periodontal pockets between 3-6 mm underwent closed root planing and laser therapy, with significant improvement observed: average pocket depth decreased from 3.35 mm to 0.59 mm after treatment.
- Statistical analysis showed a mean reduction of 2.63 mm in pocket depth (highly significant), but no notable differences based on the type of periodontal pocket were found.