Publications by authors named "Wenxiu Peng"
Article Synopsis
- A study examined the characteristics of a pathogen linked to foodborne and intramammary infections in dairy farms in Henan province and Inner Mongolia, China, focusing on factors like biofilm formation and antimicrobial resistance.
- In Henan, 60.7% of tested milk samples contained isolates, with 25.7% showing multidrug resistance, while 17.4% of samples from Inner Mongolia contained isolates, with 20.8% exhibiting similar resistance.
- Molecular typing revealed different dominant strains in each region, and phylogenetic analysis suggested potential cross-contamination on farms, emphasizing the need for better monitoring and control to reduce risks associated with these pathogens in raw milk.
Background: The plasma concentration of patients treated with efavirenz (EFV) 600 mg was found to exceed the upper limit of the proposed therapeutic window in most Chinese HIV-infected individuals; thus, dosage reduction of EFV to 400 mg daily warranted consideration. This study aimed to assess the pharmacodynamics of EFV 400 mg for HIV-1-infected patients in China.
Method: Twenty cART-naïve individuals were enrolled in this study.
Objective: To identify the pharmacokinetic differences of antiretroviral drugs between HIV-infected Chinese patients and patients of other race/ethnicities.
Study Design: Results from prospective, open-label pharmacokinetic studies among Chinese and historical data from other race/ethnicities.
Patients: Pharmacokinetics of six commonly used antiretroviral drugs, including zidovudine, lamivudine, tenofovir disoproxil fumarate, nevirapine, efavirenz and lopinavir/ritonavir, was evaluated in HIV-infected Chinese patients and compared with historical data from other race/ethnicities.
Breast milk concentration of hydroxychloroquine in Chinese lactating women with connective tissue diseases.
Eur J Clin Pharmacol
November 2019
Purpose: Considering the very limited while varying information about the excretion of hydroxychloroquine (HCQ) into human milk, we sought to determine the breast milk concentrations of HCQ in Chinese lactating patients with connective tissue diseases to assess the safety of HCQ in infants of this population.
Methods: Breastfeeding women who had been on HCQ for at least 1 year were recruited. Milk samples were collected at five time points over 12 h.