J Environ Health Sci Eng
December 2024
is a versatile model organism for exploring complex biological systems. Microbes and the external environment can affect the nervous system and drive behavioral changes in . For better survival, may develop behavioral immunity to avoid potential environmental pathogens.
View Article and Find Full Text PDFHydrogel nanophotonic devices exhibit attractive tunable capabilities in structural coloration and optical display. However, current hydrogel-based tunable strategies are mostly based on a single physical mechanism, and it remains a challenge to merge multiple mechanisms for active devices with integrated functionalities. Here, a hydrogel metagrating combining Fabry-Pérot (FP) resonance and diffraction effects is proposed for achieving tunable absorption and dynamic wavelength-selective beam steering.
View Article and Find Full Text PDFAngew Chem Int Ed Engl
October 2024
Integrating quantum dots (QDs) into polymer matrix to form nanocomposites without compromising the QD photoluminescence (PL) is crucial to emerging QD light-emitting and solar energy conversion fields. However, the most widely-used bulk polymerization technique, where monomers serve as the QD solvent, usually leads to QD PL quenching caused by radical initiators. Here we demonstrate high-brightness nanocomposites with near-unity PL quantum yield (QY), through a novel QDs-catalyzed (-initiated) bulk polymerization without using any radical initiators.
View Article and Find Full Text PDFIn this paper, we propose a multiband adjustable metamaterial absorption device based on a Dirac semimetal (BDS) AlCuFe and a thermally controlled phase-change material VO. The absorption device has an axially symmetric structure, resulting in polarization-independent characteristics, and when VO is in a high-temperature metal state, ultra-high absorption rates and sensitives at frequencies of = 2.89 THz, = 7.
View Article and Find Full Text PDFGlucose-stimulated insulin secretion (GSIS) from pancreatic beta cells is a principal mechanism for systemic glucose homeostasis, of which regulatory mechanisms are still unclear. Here we show that kinesin molecular motor KIF5B is essential for GSIS through maintaining the voltage-gated calcium channel Ca1.2 levels, by facilitating an Hsp70-to-Hsp90 chaperone exchange to pass through the quality control in the endoplasmic reticulum (ER).
View Article and Find Full Text PDFDoping of colloidal nanocrystals offers versatile ways to improve their optoelectronic properties, with potential applications in photocatalysis and photovoltaics. However, the precise role of dopants on the interfacial charge transfer properties of nanocrystals remains poorly understood. Here, we use a Cu-doped InP@ZnSe quantum dot as a model system to investigate the dopant effects on both the intrinsic photophysics and their interfacial charge transfer by combining time-resolved transient absorption and photoluminescent spectroscopic methods.
View Article and Find Full Text PDFElectrochemical hydrogenation of aldehyde molecules, exemplified by 5-hydroxymethylfurfural (HMF), offers a sustainable approach for synthesizing higher value-added alcohols. However, severe coupling side reactions impede its practical implementation at high concentrations. In this work, a cluster-level heterostructure of a PMo/Cu catalyst is synthesized by loading Keggin-type phosphomolybdic acid (HPMoO, PMo) onto Cu nanowires.
View Article and Find Full Text PDFRecently, pulsed electrolysis has been demonstrated as an emerging electrochemical technique that significantly promotes the performance of various electrocatalysis applications. The ionic nature of aqueous electrolytes implies a likely change in ionic distribution under these alternating potential conditions. However, despite the well-known importance of cations, the impact of pulsed electrolysis on the cation distribution remains unexplored as well as its influences on the performance.
View Article and Find Full Text PDFAn MXene material absorbs visible and IR light which makes a MXene-based solar absorber an ideal absorber. Here, we propose a high-absorption broadband absorber based on an array of MXene composite cylinder ring structures. The structure designed in this article fully utilizes the MXene material's large surface area to volume ratio, and in the wavelength range of 300-5000 nm, the average absorption efficiency is as high as 98.
View Article and Find Full Text PDFUpconversion (UC) of incoherent near-infrared (NIR) photons to visible photons through sensitized triplet-triplet annihilation (TTA) shows great potential in solar energy harvesting, photocatalysis, and bioimaging. However, the efficiencies of NIR-to-visible TTA-UC systems lag considerably behind those of their visible-to-visible counterparts. Here, we report a novel NIR-to-yellow TTA-UC system with a record quantum yield (QY) of 21.
View Article and Find Full Text PDFA scheme for high-efficiency transfer of optical vortices is proposed by an inelastic two-wave mixing (ITWM) process in an inverted-Y four-level atomic medium, which is originally prepared in a coherent superposition of two ground states. The orbital angular momentum (OAM) information in the incident vortex probe field can be transferred to the generated signal field through the ITWM process. Choosing reasonable experimentally realizable parameters, we find that the presence of the off-resonance control field can greatly improve the conversion efficiency of optical vortices, rather than in the absence of a control field.
View Article and Find Full Text PDFIn this study, we proposed a bifunctional sensor of high sensitivity and slow light based on carbon nanotubes (CNTs). An array of left semicircular ring (LSR), right semicircular ring (RSR), and circular ring (CR) resonators are utilized to form the proposed metamaterial. The proposed structure can achieve double plasmon-induced transparency (PIT) effects under the excitation of a TM-polarization wave.
View Article and Find Full Text PDFFront Biosci (Landmark Ed)
April 2024
Background: Immune escape is a key factor influencing survival rate of lung adenocarcinoma (LUAD) patients, but molecular mechanism of ubiquitin binding enzyme E2T (UBE2T) affecting immune escape of LUAD remains unclear. The objective was to probe role of UBE2T in LUAD.
Methods: Bioinformatics means were adopted for analyzing UBE2T and forkhead box A1 (FOXA1) expression in LUAD tissues, the gene binding sites, the pathway UBE2T regulates, and the correlation between UBE2T and glycolysis genes.
In this paper, we propose a borophene-based grating structure (BBGS) to realize multi-band plasmon-induced absorption. The coupling of two resonance modes excited by upper borophene grating (UBG) and lower borophene grating (LBG) leads to plasmon-induced absorption. The coupled-mode theory (CMT) is utilized to fit the absorption spectrum.
View Article and Find Full Text PDFBackground: The incidence of endocrine-related cancer, which includes tumors in major endocrine glands such as the breast, thyroid, pituitary, and prostate, has been increasing year by year. Various studies have indicated that brominated flame retardants (BFRs) are neurotoxic, endocrine-toxic, reproductive-toxic, and even carcinogenic. However, the epidemiological relationship between BFR exposure and endocrine-related cancer risk remains unclear.
View Article and Find Full Text PDFUnderstanding the reconstruction of electrocatalysts under operational conditions is essential for studying their catalytic mechanisms and industrial applications. Herein, using spatiotemporally resolved Raman spectroscopy with CO as a probe molecule, we resolved the spontaneous reconstruction of Cu active sites during cathodic CO reduction reactions (CORRs). Quasi-in situ focused ion beam transmission electron microscopy (FIB-TEM) revealed that under prolonged electrolysis, the Cu surface can reconstruct to form nanometer-sized Cu particles with (111)/(100) facets and abundant grain boundaries, which strongly favor the formation of an inactive *CO binding site and deteriorate the CORR performance.
View Article and Find Full Text PDFWe proposed a triple-band narrowband device based on a metal-insulator-metal (MIM) structure in visible and near-infrared regions. The finite difference time domain (FDTD) simulated results illustrated that the absorber possessed three perfect absorption peaks under TM polarization, and the absorption efficiencies were about 99.76%, 99.
View Article and Find Full Text PDFBackground: Lung squamous cell carcinoma (LUSC) has a poor prognosis and lacks appropriate diagnostic and treatment strategies. Apoptosis dysregulation is associated with tumor occurrence and drug resistance, but the prognostic value of apoptosis-related genes (ARGs) in LUSC remains unclear.
Methods: Using univariate Cox regression, least absolute shrinkage and selection operator (LASSO) regression, and multivariate Cox regression analysis based on differentially expressed ARGs, we constructed an ARG-related prognostic model for LUSC survival rates.
Disinfection by-products (DBPs), including trihalomethanes (THMs) and haloacetic acids (HAAs), have attracted attention due to their carcinogenic properties, leading to varying conclusions. This meta-analysis aimed to evaluate the dose-response relationship and the dose-dependent effect of DBPs on cancer risk. We performed a selective search in PubMed, Web of Science, and Embase databases for articles published up to September 15th, 2023.
View Article and Find Full Text PDFAumolertinib, as a novel third-generation epidermal growth factor receptor tyrosine kinase inhibitor (-TKI), has been widely employed as a first-line treatment for advanced non-small cell lung cancer (NSCLC) patients with mutation. However, reports regarding the benefit of using aumolertinib as a monotherapy in pulmonary giant cell carcinoma are relatively scarce. In this report, we present a pulmonary giant cell carcinoma case harboring the Leu858Arg (L858R) mutation, with the patient at stage cT2bN3M1c IVB.
View Article and Find Full Text PDFTwo-step deposition method has been widely exploited to fabricate FA Cs PbI perovskite solar cells. However, in previous studies, CsI is mainly added into the PbI precursor with DMF/DMSO as solvent. Here in this study, a novel method to fabricate FA Cs PbI perovskite has been proposed.
View Article and Find Full Text PDFPerfluoroalkyl and polyfluoroalkyl substance (PFAS) is a large group of fluorinated synthetic chemicals, e.g., perfluorooctanoic acid (PFOA), perfluorooctanesulfonic acid (PFOS), perfluorohexanesulfonic acid (PFHxS), perfluorodecanoic acid (PFDA), and perfluorononanoic acid (PFNA).
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