Publications by authors named "Wenxiao Zhuo"
Aim: This study aims to investigate the prevalence of intestinal pathogenic Escherichia coli (InPEC) in healthy pig-related samples and evaluate the potential virulence of the InPEC strains.
Methods And Results: A multiplex PCR method was established to identify different pathotypes of InPEC. A total of 800 rectal swab samples and 296 pork samples were collected from pig farms and slaughterhouses in Hubei province, China.
Developing nonantibiotic livestock growth promoters attracts intensive interest in the post-antibiotic era. In this study, we investigated the growth-promoting efficacy of Zhenqi granules (ZQ) in pigs and further explored the possible mechanisms by transcriptomics analysis. Weaned piglets (52 days old with an average body weight of 17.
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- The study focuses on developing a new combinatorial vaccine (Bac-sub) for porcine contagious pleuropneumonia (PCP), which is caused by APP and leads to significant economic losses in the swine industry.
- The Bac-sub vaccine combines inactivated bacterial cells and recombinant protoxins, showing no side effects and inducing more robust immune responses compared to commercial vaccines in mice.
- When challenged with virulent strains, Bac-sub provided superior protection and reduced lung bacterial loads and symptoms in both mice and pigs, proving to be a promising alternative for preventing PCP.
There has been increasing concern that the overuse of antibiotics in livestock farming is contributing to the burden of antimicrobial resistance in people. Farmed animals in Europe and North America, particularly pigs, provide a reservoir for livestock-associated methicillin-resistant Staphylococcus aureus (LA-MRSA ST398 lineage) found in people. This study is designed to investigate the contribution of MRSA from Chinese pig farms to human infection.
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