Publications by authors named "Wenxia Ding"
Objective: Compare the effects of three sampling methods on the microbiological monitoring results after reprocessing of gastrointestinal endoscopes, providing scientific basis for improving the monitoring quality of gastrointestinal endoscope cleaning and disinfection.
Method: Gastrointestinal endoscopes after reprocessing were selected randomly at the gastrointestinal endoscopy center of a tertiary hospital in Shanghai from October 2018 to February 2019. The endoscopes selected were all sampled in three different methods under continuous sampling and intermittent sampling respectively.
: To investigate the thrombolysis with recombinant human prourokinase (rhPro-UK) on thromboembolic stroke in rats at different therapeutic time windows (TTW). : Rats were subjected to embolic middle cerebral artery occlusion. RhPro-UK and positive control drugs rt-PA,UK were administered 3 h, 4.
View Article and Find Full Text PDFThe aim of the present study was to investigate the efficacy of recombinant human prourokinase (rhPro-UK) on thromboembolic stroke in rabbits. A total of 210 rabbits were used in experiments. The 180 thromboembolic stroke rabbits were divided into three therapeutic time windows with six groups in each time window (n=10).
View Article and Find Full Text PDFArticle Synopsis
- - The study assessed the effectiveness and safety of human recombinant prourokinase (rhpro-UK) in treating thromboembolic stroke in rats, comparing it to saline and other treatments like urokinase and rt-PA.
- - Results showed that rhpro-UK significantly improved neurological function and reduced brain lesions and infarct areas in a dose-dependent manner, with no increased risk of intracerebral hemorrhage.
- - Overall, rhpro-UK demonstrated protective effects against cerebral ischemia without causing additional bleeding in the rat model.