Publications by authors named "Wenxi Dang"

Article Synopsis
  • The study examines how changes in body composition before and after cetuximab treatment relate to outcomes in patients with advanced colorectal cancer.
  • A retrospective analysis of 81 patients was conducted using quantitative CT scans to measure body composition, focusing on visceral fat, muscle area, and bone density.
  • Key findings indicate that increased CEA levels and unfavorable changes in visceral fat and muscle mass are linked to poorer prognostic outcomes in these patients.
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  • The study investigates the link between β adrenergic receptor autoantibodies (β-AA) and microvascular obstruction (MVO) in patients who experienced a STEMI and underwent PCI.
  • Patients with MVO had significantly higher β-AA levels compared to those without, indicating a strong relationship.
  • Combining β-AA with other biomarkers like pNT-proBNP and pTNI enhances the ability to predict MVO risk, suggesting a more effective approach for evaluating patient prognosis after primary PCI.
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Background: Bevacizumab induces muscle atrophy by changing the gene expression level of muscle tissue. Quantitative computed tomography (QCT) enables precise measurement of various body compositions, including muscle area.

Materials & Methods: A total of 102 patients with metastatic colorectal cancer (mCRC) undergoing first-line chemotherapy based on bevacizumab were enrolled at thirst Affiliated Hospital of the University of Science and Technology of China.

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Background: β -adrenergic receptor autoantibody (β -AA) are widely present in patients with many different types of cardiovascular diseases. Proximal left anterior descending (LAD) artery lesions are associated with adverse prognostic events in patients with ST-segment elevation myocardial infarction (STEMI).

Hypothesis: β -AA is associated with the presence of proximal LAD lesions in patients with STEMI.

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Background: Acute myocardial infarction (AMI) is the most prevalent cause of mortality and morbidity in patients with type 2 diabetes mellitus (T2DM). However, strict blood glucose control does not always prevent the development and progression of AMI. Therefore, the present study aimed to explore potential new biomarkers associated with the occurrence of AMI in T2DM patients.

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Article Synopsis
  • Elevated triglyceride-glucose (TyG) index and N-terminal pro-B-type natriuretic peptide (NT-proBNP) are linked to a higher risk of major adverse cardio-cerebral events (MACCEs) in diabetic patients with acute coronary syndrome (ACS).
  • The study analyzed data from over 5,000 ACS patients with diabetes to assess the individual and combined impacts of TyG index and NT-proBNP levels on MACCEs risk.
  • Results showed that both elevated TyG index and high NT-proBNP levels were significantly associated with an increased risk for MACCEs, especially when both markers were elevated, indicating they can improve risk assessment in clinical settings.
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Purpose: Lymphocyte-monocyte ratio (LMR) has previously been used as a prognostic predictor in various solid tumors. This research aims in comparing the prognostic predictive Please check and conability of several inflammatory parameters and clinical parameters to validate further the excellent prognostic value of LMR in patients with gastric cancer treated with apatinib.

Methods: Monitor inflammatory, nutritional parameters and tumor markers.

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There is controversy in clinical application of antiplatelet drugs by monitoring platelet function. Therefore, we explored whether early and dynamic medication could bring better clinical outcomes for patients under the guidance of platelet function tests (PFT).In this retrospective cohort study, we analyzed the prognostic events of 1550 patients with acute coronary syndrome (ACS) at Tianjin People's Hospital in China.

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Chlorophenols (CPs) are important pollutants detected frequently in the environment. This study intended to detect the inhibitory effects of fourteen CPs (2-CP, 3-CP, 4-CP, 4C2AP, 4C3MP, 2.4-DCP, 2.

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