To improve the viability of Lacticaseibacillus rhamnosus ZFM231 strain in the gastrointestinal tract and exhibit better probiotic effect, an internal emulsification/gelation technique was employed to encapsulate this strain using whey protein and pectin as wall materials to fabricate the double layer microcapsules. Four key factors affecting the encapsulation process were optimized using single factor analysis and response surface methodology. Encapsulation efficiency of L.
View Article and Find Full Text PDFBackground: Clopidogrel is a traditional P2Y12 receptor inhibitor that is widely used in clinical practice, but there are significant individual differences in its therapeutic effect. Carriers of the deletion allele have a higher risk of adverse cardiovascular events than non-carriers.
Methods: In this study, 170 patients diagnosed with coronary heart disease (CHD) and on regular oral clopidogrel or ticagrelor antiplatelet therapy in the Department of Cardiology of Wuxi Second People's Hospital from August to December 2019 were screened.
Objective Iodothyronine deiodinases (DIOs) are important selenoproteins that play a key role in the bone and joint diseases. Osteoarthritis (OA) is the most prevalent joint disease especially in elders. This bioinformatic analysis was performed to explore the role of DIOs in OA pathogenesis.
View Article and Find Full Text PDFZhongguo Yi Xue Ke Xue Yuan Xue Bao
April 2022
Objective To investigate the relationship between the expression of glutathione peroxidase(GPX)genes and the clinical prognosis in glioma patients,and to construct and evaluate the model for predicting the prognosis of glioma. Methods The clinical information and GPX expression of 663 patients,including 153 patients of glioblastoma(GBM)and 510 patients of low-grade glioma(LGG),were obtained from The Cancer Genome Atlas(TCGA)database.The relationship between GPX expression and patient survival was analyzed.
View Article and Find Full Text PDFEnzymatic hydrolysate of the crude polysaccharide (SFP) extracted from Sargassum fusiforme was purified by column DEAE-52 and Sephadex G-100 to yield four components, namely, ESFP1, ESFP2, ESFP3 and ESFP4. These components were characterized by chemical composition assay, GC/MS, HPGPC, UV and FT-IR techniques. The in vitro antioxidant activities of the four purified fractions were investigated by measuring their radical scavenging activity and reducing power.
View Article and Find Full Text PDFTo explore the potential application of enzymatic degraded polysaccharides from Enteromorpha prolifra (EEP) as antioxidant in fish oils, a stable fish oil emulsion system incorporating EEP was established. Effects of emulsifier (Tween 80, gum arabic and lecithin) and EEP concentration on the physical characteristics of fish oil emulsions were investigated. The results indicated that Tween 80 was the best choice, and 1% (w/w) of EEP was the optimum concentration for the preparation of fish oil emulsions.
View Article and Find Full Text PDFZhejiang Da Xue Xue Bao Yi Xue Ban
July 2017
Objective: To investigate the effect of low-salt diet on gene expression of canine cardiac tissue.
Methods: Microarray data (GSE17149) of heart tissue from dogs fed with low-salt diet was obtained from the Gene Expression Omnibus (GEO). The data were analyzed by Qlucore Omics Explorer 3.
A compact fiber polarizer is demonstrated by the filling of selected air holes of a hollow-core photonic crystal fiber (PCF) with a liquid. The liquid-filling results in an asymmetric waveguide structure, leading to a large polarization dependent loss. A 6 mm long ethanol-filled PCF exhibits a polarization extinction ratio of ∼18 dB over a wavelength range from 1480 nm to 1600 nm.
View Article and Find Full Text PDFA compact temperature sensor based on a fiber loop mirror (FLM) combined with an alcohol-filled high-birefringence photonic crystal fiber (PCF) is proposed and experimentally demonstrated. The output of the FLM is an interference spectrum with many resonant dips, of which the wavelengths are quite sensitive to the change of the refractive index of the filled alcohol for the interference of the FLM. Simulation analysis predicts a high temperature sensitivity, and experimental results show it reaches up to 6.
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