Publications by authors named "Wentian Song"
Article Synopsis
- Food-derived peptides, particularly from peanuts, have been studied as effective inhibitors of angiotensin-converting enzyme (ACE), which plays a role in hypertension and cardiovascular health.
- The research involved both in vitro tests and computational methods to confirm the peptides' inhibitory effects and understand their mechanisms of action.
- Among the tested peptides, FPHPP was identified as the most potent, demonstrating strong binding affinity and beneficial effects on cell health markers related to oxidative stress and inflammation.
This work aimed to investigate whether there are synergistic effects between walnut peptide (WNP) and ginseng extracts (GSE) treatments to ameliorate the memory impairment caused by scopolamine (SCOP). The Morris water maze trial, hippocampal neuron morphology, neurotransmitters, and synaptic ultrastructure were examined, along with brain-derived neurotrophic factor (BDNF)-related signaling pathway proteins. The results of the Morris water maze trial demonstrated that the combined administration of WNP and GSE effectively alleviated memory impairment in C57BL/6 rats caused by SCOP.
View Article and Find Full Text PDFThe plastein reaction can increase the activity of angiotensin-converting enzyme (ACE) inhibitory peptides, but the underlying mechanism is unknown. Hence, hazelnut protein hydrolysate and hazelnut peptide YLVR were used as substrate to explore the effect of plastein on physicochemical properties and the mechanism of structural change. The increase in turbidity and particle size and the decrease in free amino groups indicated that the reaction occurred via condensation.
View Article and Find Full Text PDF