Interrupted time series analysis using the ARIMA model of the impact of COVID-19 on the incidence rate of notifiable communicable diseases in China.

Background: The coronavirus disease 2019 (COVID-19) pandemic in China is ongoing. Some studies have shown that the incidence of respiratory and intestinal infectious diseases in 2020 decreased significantly compared with previous years. Interrupted time series (ITS) is a time series analysis method that evaluates the impact of intervention measures on outcomes and can control the original regression trend of outcomes before and after the intervention.

Trends in hepatitis B notification rates in Guangzhou, China, between 2009 and 2020: an epidemiological study.

Background: Although the prevalence of hepatitis B in Guangzhou, China, is high, the epidemiological trends are not well-documented. We aimed to analyse newly reported hepatitis B cases in Guangzhou between 2009 and 2020 to explore the epidemiological trends and provide insights for the development of control measures.

Methods: Information on the population and new cases of hepatitis B in Guangzhou between 2009 and 2020 was obtained from the China Information System for Disease Control and Prevention, which was used to calculate the annual notification rates of hepatitis B by sex, age group (0-9; 10-19; 20-29; 30-39; 40-49; 50-59; ≥ 60 years), and location (urban or rural).

Travel-related infection in Guangzhou, China,2009-2019.

Background: We analyzed the epidemiological characteristics of travel-related infectious diseases in reported Guangzhou between 2009 and 2019 to provide a scientific basis for prevention and control strategies.

Method: The infectious diseases report information system of China was mined for case reports, combined with clinical diagnosis records, and analyzed.

Results: Between 2009 and 2019, 1478 cases of imported infectious diseases were reported in Guangzhou.

Rotavirus Gastroenteritis Infection Among Children Vaccinated and Unvaccinated With Rotavirus Vaccine in Southern China: A Population-Based Assessment.

Importance: Since 2000, the Lanzhou lamb rotavirus vaccine has been exclusively licensed in China for voluntary rotavirus gastroenteritis (RV-GE) prevention.

Objective: To evaluate the association of the Lanzhou lamb rotavirus vaccination with RV-GE among children in southern China.

Design, Setting, And Participants: This cross-sectional, ecological study was set in Guangzhou, China.

The effects of meteorological factors on influenza among children in Guangzhou, China.

Background: Influenza seriously affects the health of children, yet little evidence is available on the association between meteorological factors and the occurrence of influenza among children in subtropical regions. The current study aimed to explore the effects of meteorological factors on influenza among children in Guangzhou, a subtropical city in China.

Methods: The distributed lag nonlinear model (DLNM) was used to assess the effects of meteorological factors on children influenza occurrence in Guangzhou, China.

The relationship between meteorological factors and mumps incidence in Guangzhou, China, 2005-2012:

Background: Over the past decade, there have been resurgences and large-scale outbreaks of mumps worldwide. Little evidence is available on the relationship between meteorological factors and the incidence of mumps. We aimed to explore the effects of meteorological factors on mumps incidence.

Measles epidemic from 1951 to 2012 and vaccine effectiveness in Guangzhou, southern China.

Background: Since the National Expanded Program on Immunization was implemented in China, considerable progress has been made in reducing the incidence of measles. However, the incidence of measles increased again in 2004. Few post-marketing studies on measles vaccine effectiveness were reported in China.

The effects of weather conditions on measles incidence in Guangzhou, Southern China.

Background: Few studies were conducted to examine the effects of weather conditions on the incidence of measles.

Methods: We used a distributed lag nonlinear model (DLNM) to analyze the relationship between meteorological factors and measles incidence in Guangzhou, China.

Results: Nonlinear effects of temperature and relative humidity on measles incidence were observed.

Seasonal influenza vaccine effectiveness among children, 2010-2012.

Background: The annual differences in the seasonal influenza vaccine and the circulating strains make it necessary to assess influenza vaccine effectiveness (VE) yearly. We assessed the effectiveness of the trivalent inactivated influenza vaccine for the 2010-2011 and 2011-2012 influenza seasons among children in Guangzhou, China.

Methods: We conducted a 1:2 matched case-control study based on date of birth (±7 days), gender, and area of residence.

Effectiveness of one dose of mumps vaccine against clinically diagnosed mumps in Guangzhou, China, 2006-2012.

Although mumps-containing vaccines were introduced in China in 1990s, mumps continues to be a public health concern due to the lack of decline in reported mumps cases. To assess the mumps vaccine effectiveness (VE) in Guangzhou, China, we performed a 1:1 matched case-control study. Among children in Guangzhou aged 8 mo to 12 y during 2006 to 2012, we matched one healthy child to each child with clinically diagnosed mumps.

Effectiveness of seasonal influenza vaccine against clinically diagnosed influenza over 2 consecutive seasons in children in Guangzhou, China: a matched case-control study.

Influenza vaccine has to be reformulated each year due to the ever-changing antigenicity of the influenza virus. However, few post-licensure studies of influenza vaccine are available in China. We aimed to measure the effectiveness of seasonal influenza vaccine during 2 consecutive seasons.

Effectiveness of the Lanzhou lamb rotavirus vaccine against gastroenteritis among children.

The Lanzhou lamb rotavirus (LLR) vaccine has been in use in China since 2000. This study evaluated this vaccine's effectiveness using a case-control design in Guangzhou. In the study area, there were 3130 laboratory-confirmed rotavirus gastroenteritis cases in children between 2 and 35 months old from 2009 to 2011.

A two-year surveillance of 2009 pandemic influenza A (H1N1) in Guangzhou, China: from pandemic to seasonal influenza?

In this two-years surveillance of 2009 pandemic influenza A (H1N1) (pH1N1) in Guangzhou, China, we reported here that the scale and duration of pH1N1 outbreaks, severe disease and fatality rates of pH1N1 patients were significantly lower or shorter in the second epidemic year (May 2010-April 2011) than those in the first epidemic year (May 2009-April 2010) (P<0.05), but similar to those of seasonal influenza (P>0.05).