Bioactive MXene Promoting Angiogenesis and Skeletal Muscle Regeneration through Regulating M2 Polarization and Oxidation Stress.

Complete repair of skeletal muscles caused by severe mechanical damage and muscle-related diseases remains a challenge. 2D Ti C T (MXene) possesses special photoelectromagnetic properties and has attracted considerable attention in materials science and engineering. However, the bioactive properties and potential mechanism of MXene in tissue engineering, especially in skeletal muscle regeneration, are unclear.

Automatic identification of harmful algae based on multiple convolutional neural networks and transfer learning.

The monitoring of harmful phytoplankton is very important for the maintenance of the aquatic ecological environment. Traditional algae monitoring methods require professionals with substantial experience in algae species, which are time-consuming, expensive, and limited in practice. The automatic classification of algae cell images and the identification of harmful phytoplankton images were realized by the combination of multiple convolutional neural networks (CNNs) and deep learning techniques based on transfer learning in this work.

Bioactive anti-inflammatory antibacterial metformin-contained hydrogel dressing accelerating wound healing.

Highly efficient wound healing and skin regeneration remain a challenge. Long-term inflammation and bacterial infection can inhibit the healing process and lead to the scar formation. Here, we report a hydrogel (FEM) formed by self-assembly of ε-poly-l-lysine-F127-ε-poly-l-lysine (EPL-F127-EPL) and metformin for wound repair.

Impacts of Regional Speed Control Strategy Based on Macroscopic Fundamental Diagram on Energy Consumption and Traffic Emissions: A Case Study of Beijing.

Numerous studies shown that particulate matter in the ambient environment has a significant impact on the health of the respiratory system. To understand the interrelationships between urban built environment, transportation operations and health, this study proposes an innovative approach that uses real-world GPS datasets to calculate energy consumption and emissions from transportation. The experiment used the traffic operation state in the Fourth Ring Road of Beijing as the research object and tested the impact of using the Regional speed optimization (RSO) strategy based on Macroscopic Fundamental Diagram (MFD) on energy consumption and emissions during peak hours.

Transcriptomic Responses of Serovars Enteritidis in Sodium Hypochlorite.

serovars Enteritidis (. Enteritidis) can survive extreme food processing environments including bactericidal sodium hypochlorite (NaClO) treatments generally recognized as safe. In order to reveal the molecular regulatory mechanisms underlying the phenotypes, the overall regulation of genes at the transcription level in .

Evaluation of SARS-COV-2 transmission and infection in airliner cabins.

Commercial airliners have played an important role in spreading the SARS-CoV-2 virus worldwide. This study used computational fluid dynamics (CFD) to simulate the transmission of SARS-CoV-2 on a flight from London to Hanoi and another from Singapore to Hangzhou. The dispersion of droplets of different sizes generated by coughing, talking, and breathing activities in a cabin by an infected person was simulated by means of the Lagrangian method.

Insights from label free-based proteomic analysis into inhibitory effects ε-Poly-lysine against Vibrio parahaemolyticus.

Vibrio parahaemolyticus is one of the most common pathogenic bacteria that pose a threat to human health. The purpose of this study was to investigate antibacterial mechanisms of ε-poly-lysine (ε-PL) against V. parahaemolyticus using a lable free-based proteomic analysis.

A Neural Recording and Stimulation Chip with Artifact Suppression for Biomedical Devices.

This paper presents chip implementation of the integrated neural recording and stimulation system with stimulation-induced artifact suppression. The implemented chip consists of low-power neural recording circuits, stimulation circuits, and action potential detection circuits. These circuits constitute a closed-loop simultaneous neural recording and stimulation system for biomedical devices, and a proposed artifact suppression technique is used in the system.

(Ni,Co)Se@Ni(OH) heterojunction nanosheets as an efficient electrocatalyst for the hydrogen evolution reaction.

A heterogeneous structure formed by coupling two or more phases can reinforce the activity of active sites and expedite electron transfer, which is conducive to boosting its electrocatalytic activity. Herein, we designed nickel foam supported (NiCo)Se@Ni(OH) (NCS@NH) heterojunction nanosheets by a two-step method. First of all, the NiCoS@Ni(OH) (NiCoS@NH) nanosheets coated on nickel foam were acquired via a hydrothermal method.

Ni P Interlayer and Mn Doping Synergistically Expedite the Hydrogen Evolution Reaction Kinetics of Co P.

Transition metal phosphide is regarded as one of the most promising candidates to replace noble-metal hydrogen evolution reaction (HER) electrocatalysts. Nevertheless, the controllable design and synthesis of transition metal phosphide electrocatalysts with efficient and stable electrochemical performance are still very challenging. Herein, a novel hierarchical HER electrocatalyst consisting of three-dimensional (3D) coral-like Mn-doped Co P@an intermediate layer of Ni P generated in situ by phosphorization on Ni foam (MnCoP/NiP/NF) is reported.

Rational Design and Controlled Synthesis of V-Doped Ni S /Ni P Heterostructured Nanosheets for the Hydrogen Evolution Reaction.

Rational construction of high-efficiency and low-cost catalysts is one of the most promising ways to produce hydrogen but remains a huge challenge. Herein, interface engineering and heteroatom doping were used to synthesize V-doped sulfide/phosphide heterostructures on nickel foam (V-Ni S /Ni P /NF) by phosphating treatment at low temperature. The incorporation of V can adjust the electronic structure of Ni S , expose more active sites, and protect the 3D structure of Ni foam from damage.

A Framework for an Indoor Safety Management System Based on Digital Twin.

With the development of the next generation of information technology, an increasing amount of attention is being paid to smart residential spaces, including smart cities, smart buildings, and smart homes. Building indoor safety intelligence is an important research topic. However, current indoor safety management methods cannot comprehensively analyse safety data, owing to a poor combination of safety management and building information.

New use for spent coffee ground as an adsorbent for tetracycline removal in water.

Spent coffee grounds (SCG-1 and SCG-2) were used to study the adsorption of tetracycline (TC) antibiotics and the effects of adsorption time, initial pH, amount of adsorbent and ionic strength were detected. The TC adsorption isotherm on SCG-1 was compared with SCG-2. The results showed that the removal efficiencies of TC (50 mg/L) of SCG-1 and SCG-2 were 83.

Tensor-Based Angle Estimation Approach for Strictly Noncircular Sources with Unknown Mutual Coupling in Bistatic MIMO Radar.

In the paper, the estimation of joint direction-of-departure (DOD) and direction-of-arrival (DOA) for strictly noncircular targets in multiple-input multiple-output (MIMO) radar with unknown mutual coupling is considered, and a tensor-based angle estimation method is proposed. In the proposed method, making use of the banded symmetric Toeplitz structure of the mutual coupling matrix, the influence of the unknown mutual coupling is removed in the tensor domain. Then, a special enhancement tensor is formulated to capture both the noncircularity and inherent multidimensional structure of strictly noncircular signals.

Utilizations of agricultural waste as adsorbent for the removal of contaminants: A review.

In recent years, various industrial activities have caused serious pollution to the environment. Due to the low operating costs and high flexibility, adsorption is considered as one of the most effective technologies for pollutant management. Agricultural waste has loose and porous structures, and contains functional groups such as the carboxyl group and hydroxyl group, so it can be invoked as biological adsorption material.

Knockdown of ARL4C inhibits osteogenic differentiation of human adipose-derived stem cells through disruption of the Wnt signaling pathway.

ADP-ribosylation factor-like 4C (ARL4C) has been shown to play an important role in cholesterol secretion, microtubule dynamics, and cell morphological changes. However, its role in osteogenesis has not been explored. In this study, we found that ARL4C is downregulated during the osteogenic differentiation of human adipose derived stem cells (hASCs).

Buildup of a highly twisted magnetic flux rope during a solar eruption.

The magnetic flux rope is among the most fundamental magnetic configurations in plasma. Although its presence after solar eruptions has been verified by spacecraft measurements near Earth, its formation on the Sun remains elusive, yet is critical to understanding a broad spectrum of phenomena. Here we study the dynamic formation of a magnetic flux rope during a classic two-ribbon flare.

RAI3 knockdown promotes adipogenic differentiation of human adipose-derived stem cells by decreasing β-catenin levels.

Retinoic acid-induced protein 3 (RAI3) has been found to play significant roles in embryonic development, cellular proliferation and differentiation, but its role in adipogenesis has not been explored. In this study, we discovered RAI3 was downregulated during the adipogenic differentiation of human adipose derived stem cells (hASCs). Moreover, we demonstrated that knockdown of RAI3 promoted adipogenic differentiation of hASCs both in vitro and in vivo.

[Quantitative evaluation of aortic regurgitation by general imaging three-dimensional quantification].

Objective: To investigate the feasibility and application value of AR-Vol measured by GI3DQ method directly.

Methods: One hundred and two patients with aortic regurgitation who underwent echocardiographic examination in Tianjin Chest Hospital from February 2014 to October 2014 were selected randomly and divided into two groups: the eccentric group included forty cases with eccentric aortic regurgitation; the central group included sixty and two cases with central aortic regurgitation. AR-Vol were directly measured by GI3DQ method, and then it was calculated by PISA method as the reference standard.

Mental Health Utilization in a Pediatric Emergency Department.

Objective: Mental health complaints are frequent in the pediatric emergency department (PED). The objective of this study was to describe trends over time in PED utilization for mental health care at in a single pediatric tertiary care hospital. It is our hypothesis that the resources used by this patient population are high and that mental health-related visits have increased over the most recent decade.

Electrical/optical dual-function redox potential transistor.

We demonstrate a new type of transistors, the electrical/optical "dual-function redox-potential transistors", which is solution processable and environmentally stable. This device consists of vertically staked electrodes that act as gate, emitter and collector. It can perform as a normal transistor, whilst one electrode which is sensitised by dye enables to generate photocurrent when illuminated.

KDM5B regulates embryonic stem cell self-renewal and represses cryptic intragenic transcription.

Although regulation of histone methylation is believed to contribute to embryonic stem cell (ESC) self-renewal, the mechanisms remain obscure. We show here that the histone H3 trimethyl lysine 4 (H3K4me3) demethylase, KDM5B, is a downstream Nanog target and critical for ESC self-renewal. Although KDM5B is believed to function as a promoter-bound repressor, we find that it paradoxically functions as an activator of a gene network associated with self-renewal.