Publications by authors named "Wensi Niu"
Article Synopsis
- Prior antibiotic exposure, particularly to carbapenems and vancomycin, is linked to a higher incidence of Ventilator-Associated Pneumonia (VAP) in children on mechanical ventilation, with VAP affecting about 21.94% of the studied population.
- The VAP group demonstrated significantly longer hospital and PICU stays, as well as increased mechanical ventilation duration compared to the non-VAP group, along with higher mortality rates (36.07% vs. 21.82%).
- Factors such as prolonged carbapenem use (≥7 days), repeated intubations, and tracheostomy emerge as independent risk factors for VAP occurrence, highlighting the need for further research on antibiotic regimes.
[Analysis of a child with Verheij syndrome due to variant of PUF60 gene].
Zhonghua Yi Xue Yi Chuan Xue Za Zhi
December 2023
Objective: To explore the clinical phenotype and genetic variant in a child with Verheij syndrome (VRJS).
Methods: A child who had presented at the Soochow University Affiliated Children's Hospital and Wujiang District Children's Hospital in July 2022 for "elevated scapula since early childhood" was selected as the study subject. Peripheral blood samples of the child and his parents were collected and subjected to whole exome sequencing.
Objective: We aimed to develop a nomogram to predict the risk of severe influenza in previously healthy children.
Methods: In this retrospective cohort study, we reviewed the clinical data of 1135 previously healthy children infected with influenza who were hospitalized in the Children's Hospital of Soochow University between 1 January 2017 and 30 June 2021. Children were randomly assigned in a 7:3 ratio to a training or validation cohort.
Human respiratory syncytial virus (RSV) is the major cause of acute lower respiratory tract infections worldwide in infants and young children. The RSV F glycoprotein is a class I fusion protein that mediates viral entry into host cells and is a major target of neutralizing antibodies. Targeting F glycoprotein has been recognized as a promising antiviral therapeutic strategy against RSV infection.
View Article and Find Full Text PDFObjective: To determine the risk factors for delayed radiographic resolution in children with refractory pneumonia (RMPP) and explore the most suitable time for interventional bronchoscopy.
Methods: This retrospective study involved 142 children with RMPP who were admitted to our hospital from 1 January 2015 to 31 December 2017. They were divided into a common resolution group and a delayed resolution group based on their chest radiograph series.