Gender Differences in the Relationship Between Short-Form Video Addiction and Adolescent Depression: The Mediating Role of Attentional Bias.

Previous studies have shown that short-form video addiction (SVA) is a significant predictor of adolescent depression. However, little is known about the mediating mechanisms. Guided by the Interaction of Person-Affect-Cognition-Execution model, this study aimed to investigate the relationship between SVA and depression among Chinese adolescents and to examine the mediating role of attentional bias toward positive information (API) and negative information (ANI), including potential gender differences.

Reduce negative life events to Increase satisfaction: A daily diary study on the relationship between negative life events and life satisfaction.

Life satisfaction refers to an individual' s cognitive evaluation of the overall quality of their life considering the various aspects therein. Although the existing research has demonstrated the between-person relationship between negative life events and life satisfaction based on retrospective measures, less is known about this relationship at the within-person level. A daily diary method could examine this within-person relationship and decrease systematic recall biases.

Xanthatin suppresses proliferation and tumorigenicity of glioma cells through autophagy inhibition via activation of the PI3K-Akt-mTOR pathway.

Glioma is the most common and aggressive primary brain tumor in adults with high morbidity and mortality. Rapid proliferation and diffuse migration are the main obstacles to successful glioma treatment. Xanthatin, a sesquiterpene lactone purified from Xanthium strumarium L.

Genipin protects against mitochondrial damage of the retinal pigment epithelium under hyperglycemia through the pathway mediated by the signaling axis.

Background: To investigate the protective effect and mechanism of genipin (GE) on mitochondrial damage in retinal pigment epithelial (RPE) cells induced by high glucose.

Methods: Differential genes of GE in the treatment of diabetic retinopathy (DR) were screened by the Gene Expression Omnibus (GEO) database. Differential genes located in the pathway were obtained.

Xanthatin induces glioma cell apoptosis and inhibits tumor growth via activating endoplasmic reticulum stress-dependent CHOP pathway.

Xanthatin is a natural sesquiterpene lactone purified from Xanthium strumarium L., which has shown prominent antitumor activity against a variety of cancer cells. In the current study, we investigated the effect of xanthatin on the growth of glioma cells in vitro and in vivo, and elucidated the underlying mechanisms.