Synopsis of recent research by authors named "Wenru Zeng"
- Wenru Zeng's recent research primarily focuses on diabetic cardiomyopathy (DCM) and the therapeutic potential of traditional Chinese medicine, specifically exploring the mechanisms by which compounds like Fufang Zhenzhu Tiaozhi (FTZ) ameliorate cardiometabolic disorders and mitochondrial dysfunction in diabetic models.
- A significant aspect of Zeng's work investigates the role of the USP7 enzyme in promoting DCM and its involvement in mitochondrial homeostasis, highlighting the need for effective treatment strategies in the context of diabetes-related cardiovascular complications.
- Additionally, Zeng has contributed to understanding the cytosolic DNA sensing pathway (cGAS-STING) in the context of cardiac pyroptosis and hypertrophy, further emphasizing the intricate relationship between metabolic dysregulation and cardiovascular health issues in diabetes.
