Publications by authors named "Wenquan Li"

Article Synopsis
  • The study aimed to compare clinical characteristics and endolymphatic hydrops (ELH) manifestations between patients with delayed Ménière's disease (DMD) and classic Ménière's disease (CMD).
  • It involved analyzing data from 523 MD patients, where findings revealed that DMD patients have a higher prevalence of bilateral MD and more severe hearing loss than those with CMD.
  • Results showed that 100% of affected ears in both groups had ELH, but DMD patients had a significantly higher occurrence of contralateral ELH, indicating possible common mechanisms behind both disease types.
View Article and Find Full Text PDF

Manganese oxide (MnO) based aqueous zinc-ion batteries (AZIBs) are considered to be a promising battery for grid-scale energy storage. However, they usually suffer from the great challenge of capacity attenuation due to Mn dissolution and irreversible structural transformation. Herein, full use of the shortcomings is made to design high-performance cathode-free AZIBs.

View Article and Find Full Text PDF

Melasma, a prevalent pigmentary disorder, is characterized by its complex etiology, propensity for recurrence, and resistance to treatment. However, there is currently no research on melasma through bibliometrics and visualisation. This study analyses the hotspots and trends in the field based on 2,709 publications from the Web of Science Core Collection (WOSCC).

View Article and Find Full Text PDF

Exosome-derived microRNAs (miRNAs) are biomacromolecules and nanoscale extracellular vesicles originating from intracellular compartments that are secreted by most cells into the extracellular space. This review examines the formation and function of exosomal miRNAs in biological information transfer, explores the pathogenesis of vitiligo, and highlights the relationship between exosomal miRNAs and vitiligo. The aim is to deepen the understanding of how exosomal miRNAs influence immune imbalance, oxidative stress damage, melanocyte-keratinocyte interactions, and melanogenesis disorders in the development of vitiligo.

View Article and Find Full Text PDF

Layered double hydroxide (LDH) materials, despite their high theoretical capacity, exhibit significant performance degradation with increasing load due to their low conductivity. Simultaneously achieving both high capacity and high rate performance is challenging. Herein, we fabricated vertically aligned CuO nanowires in situ on the copper foam (CF) substrate by alkali-etching combined with the annealing process.

View Article and Find Full Text PDF

Keloids are prevalent pathological scars, often leading to cosmetic deformities and hindering joint mobility.They cause discomfort, including burning and itching, while gradually expanding and potentially posing a risk of cancer.Developing effective drugs and treatments for keloids has been a persistent challenge in the medical field.

View Article and Find Full Text PDF

The bilateral Bus Rapid Transit (BRT) system is a kind of BRT system in which the stops are located in the middle of the transit lane. By simultaneously serving transit lines in opposite directions, it is particularly designed to save space resources and enhance service quality. To improve the operational efficiency of the bilateral BRT, this paper optimizes the operational performance of bilateral BRT with elastic demand.

View Article and Find Full Text PDF
Article Synopsis
  • Clinicians are facing an influx of meta-analyses (MAs) regarding Janus kinase inhibitors (JKIs) for treating atopic dermatitis (AD), highlighting a need for clear and comprehensive evidence on their effectiveness and safety.
  • Sixteen MAs were reviewed, revealing that JKIs lead to a quicker response in terms of overall assessment (IGA) and significant improvements in eczema severity (EASI75), with most studies showing high-quality evidence for their efficacy.
  • While JKIs were generally safe, specific doses of abrocitinib showed increased risks for side effects like acne and headaches, indicating a need for careful monitoring and choice in treatment.
View Article and Find Full Text PDF
Article Synopsis
  • - The skin is the largest organ and hosts a diverse microbiota that helps protect against pathogens and supports the immune system, but imbalances in this microbiota can lead to inflammatory skin diseases (ISDs) such as psoriasis and atopic dermatitis.
  • - Changes in the skin microbiota can disrupt the skin's barrier function, leading to increased water loss and abnormal lipid metabolism, which contribute to the development of ISDs.
  • - Microorganisms can release toxins that damage the skin barrier, allowing them to enter the bloodstream and trigger immune responses, suggesting that targeting the skin microbiome could lead to new treatments for these conditions.
View Article and Find Full Text PDF

2D transition metal dichalcogenides (TMDs) have garnered significant interest as cathode materials for aqueous zinc-ion batteries (AZIBs) due to their open transport channels and abundant Zn intercalation sites. However, unmodified TMDs exhibit low electrochemical activity and poor kinetics owing to the high binding energy and large hydration radius of divalent Zn. To overcome these limitations, an interlayer engineering strategy is proposed where K is preintercalated into K-MoS nanosheets, which then undergo in situ growth on carbon nanospheres (denoted as K-MoS@C nanoflowers).

View Article and Find Full Text PDF

The advent of implantable bioelectronic devices offers prospective solutions toward health monitoring and disease diagnosis and treatments. However, advances in power modules have lagged far behind the tissue-integrated sensor nodes and circuit units. Here, we report a soft implantable power system that monolithically integrates wireless energy transmission and storage modules.

View Article and Find Full Text PDF

Flex-route transit (FRT) has significant advantages in low-demand areas. Existing studies have focused on practical experience, strategic planning, and operational planning. Few studies have addressed the effect of sociodemographic and psychological latent characteristics on the acceptance of FRT.

View Article and Find Full Text PDF

Biodegradable implantable devices are of growing interest in biosensors and bioelectronics. One of the key unresolved challenges is the availability of power supply. To enable biodegradable energy-storage devices, herein, 2D heterostructured MoO -MoS nanosheet arrays are synthesized on water-soluble Mo foil, showing a high areal capacitance of 164.

View Article and Find Full Text PDF

Objectives: To elucidate the characteristics of the clinical details and endolymphatic hydrops (EH) in bilateral Ménière's disease (BMD).

Methods: A total of 545 patients with definite MD were enrolled. Demographic variables; the age of onset; disease course; inner ear function; the coexistence of related disorders such as migraine, delayed MD, drop attacks, and autoimmune diseases; familial history; and characteristics of EH were analyzed.

View Article and Find Full Text PDF

On the one hand, considering that the traditional fatigue method of railway freight cars is based on damage as a parameter, the influence of stress waveform cannot be considered. On the other hand, physical experiments have the characteristics of lag, long period, and high cost. The full-scale physical test and virtual test of car body are carried out.

View Article and Find Full Text PDF
Article Synopsis
  • - The study discusses the challenges of bonding incompatible polymers, such as polypropylene (PP) and polyamide6 (PA6), due to poor interfacial adhesion, and introduces a solution using an interlayer solder sheet (ISS) with maleic anhydride-functionalized polypropylene.
  • - The ultrasonic welding process successfully achieved a welding strength of 22.3 MPa for the PP-PA6 combination, demonstrating significant strength retention compared to the original PP material.
  • - Advanced analytical techniques like FTIR, XRD, and SEM confirmed the formation of a PP-PA6 copolymer that improved interfacial adhesion, allowing for enhanced compatibility and fusion bonding between the two previously incompatible materials.
View Article and Find Full Text PDF

Objectives: This study aimed to investigate the perilymph metabolism by analyzing the 3D real IR MR findings in acoustic neuroma (AN) after intravenous administration of gadolinium (Gd).

Methods: Eleven patients (6 men and 5 women) diagnosed with AN were included, and 3D real IR MRI was performed 4 hours after intravenous Gd injection. The signal intensity and details of inner ear, tumor, and internal auditory canal (IAC) by MRI were analyzed.

View Article and Find Full Text PDF

Background: The outbreak of COVID-19 has resulted in serious concerns in China and abroad. To investigate clinical features of confirmed and suspected patients with COVID-19 in west China, and to examine differences between severe versus non-severe patients.

Methods: Patients admitted for COVID-19 between January 21 and February 11 from fifteen hospitals in Sichuan Province, China were included.

View Article and Find Full Text PDF

Exploring innovative solutions to improve the healthcare of the aging and diseased population continues to be a global challenge. Among a number of strategies toward this goal, tissue engineering and regenerative medicine (TERM) has gradually evolved into a promising approach to meet future needs of patients. TERM has recently received increasing attention in Asia, as evidenced by the markedly increased number of researchers, publications, clinical trials, and translational products.

View Article and Find Full Text PDF

Purpose: The best surgical method for the management of adhesive otitis media is controversial. The aim of the study was to explore the feasibility and effectiveness of tympanoplasty combined with fascia grafting catheterization in the treatment of adhesive otitis media.

Methods: This was a retrospective study of patients with adhesive otitis media and who underwent tympanoplasty combined with fascia grafting and catheterization between April 2015 and December 2016 at the Eye-Ear-Nose-Throat Hospital Affiliated to Fudan University.

View Article and Find Full Text PDF

Objectives:: The purpose of this study was to investigate the correlation between grades of endolymphatic hydrops (ELH) and clinical characteristics and determine the detailed clinical characteristics of Ménière's disease (MD) patients with evidence of hydrops based on magnetic resonance imaging (MRI).

Methods:: One hundred ninety-eight MD patients (396 ears) with MRI evidence of hydrops were included. ELH grades were evaluated using the Nakashima grading standard.

View Article and Find Full Text PDF

Focusing on the defects in the lighting color of LED lamps and the chip heat exists in the traditional LED package which caused phosphor performance degradation, color temperature drift and the uneven light, the remote phosphor package which is emerging in recent years is used in this paper. With yellow-green YGG phosphor and nitrogen red phosphors mixing with silica gel, the remote phosphor is made and then encapsulated as the LED lamps. A lot of experiments were made to determine the best ratio of yellow green phosphor, red phosphor and silica gel, LED lamps with different color temperature was prepared.

View Article and Find Full Text PDF

The treatment and disposal of sewage sludge is a growing problem for sewage treatment plants. One method of disposal is to use sewage sludge as partial replacement for raw material in cement manufacture. Although this process has been well researched, little attention has been given to the thermal properties of cement that has had sewage sludge incorporated in the manufacturing process.

View Article and Find Full Text PDF

Objective: To explore the effects of simultaneous multi-level surgery intervention on the changes of the oxidative stress and the cognitive function in young and middle-aged patients with moderate-severe OSAHS.

Method: One hundred and sixteen young and middle-aged patients with moderate-severe OSAHS received simultaneous multi-level surgery. PSG,malondialdehyde (MDA), advanced oxidation protein products (AOPP) and 8-isoprostaneF2α (8-iso-PGF2α) were tested, together with the evaluation of the questionnaires of Montreal cognitive assessment (MoCA), mini-mental state examination (MMSE) and Epworth sleepiness scale (ESS) before and 6 months after surgery.

View Article and Find Full Text PDF

Synopsis of recent research by authors named "Wenquan Li"

  • - Wenquan Li's recent research spans a diverse range of subjects, from clinical studies on Ménière's disease to innovative materials for energy storage, indicating a broad interdisciplinary focus in both medical and engineering fields.
  • - Key findings include a comparative analysis highlighting distinctive clinical features between classic and delayed Ménière's disease, advancements in cathode-free aqueous zinc-ion battery technology to mitigate capacity loss, and reviews on the role of exosomal microRNAs in vitiligo's pathogenesis and microbiome influences on inflammatory skin diseases.
  • - Li's work also examines significant trends in melasma research using bibliometrics, evaluates the effectiveness of Janus kinase inhibitors for treating atopic dermatitis through meta-analyses, and develops new composite structures for high-performance supercapacitors, showcasing a commitment to addressing both health and technological challenges.