Publications by authors named "Wenqiong Xu"

By virtue of CiteSpace, this study aims to evaluate and pinpoint the status, hot areas, and frontiers of growth-mindset research. Co-authorship analysis, co-citation analysis, co-occurrence analysis, cluster analysis, and content analysis are conducted, based on 543 articles selected from the Social Sciences Citation Index database. Researchers from Australia and countries/territories in North America, East Asia, and Western Europe have maintained relatively closer cooperation with each other.

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Background: Robotic surgery (RS) is gaining popularity; however, evidence for abdominoperineal resection (APR) of rectal cancer (RC) is scarce.

Aim: To compare the efficacy of RS and laparoscopic surgery (LS) in APR for RC.

Methods: We retrospectively identified patients with RC who underwent APR by RS or LS from April 2016 to June 2022.

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Article Synopsis
  • Immune checkpoint inhibitors (ICPis) like toripalimab are new cancer treatment drugs that can cause serious side effects, including diabetes mellitus.
  • A case study in southern China highlights that diabetes is a rare but life-threatening complication that can arise after toripalimab treatment, with only one similar case previously reported in the country.
  • Clinicians should closely monitor patients for this adverse effect, as insulin therapy may be required to manage ICPis-related diabetes and prevent severe complications like diabetic ketoacidosis.
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Diabetic nephropathy (DN) is the primary reason of chronic kidney disease. The aim of our study is to explore the role and action mechanism of M2 macrophage-derived exosomes in high glucose (HG)-induced podocytes injury. Here, 30 mmol/L of HG was used to induce podocytes injury.

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The present study was designed to investigate the role of nicotinamide phosphoribosyltransferase (Nampt) overexpression in a rat model of Hashimoto's thyroiditis (HT) and its mechanism of action. A rat model of HT was constructed, and the HT rats were injected with an adenoviral expression vector carrying the gene. The expression of Nampt and Toll-like receptor 4 (TLR4) in thyroid tissues was examined using immunohistochemistry (IHC), RT-qPCR and western blot analyses.

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Bscl2 mice recapitulate many of the major metabolic manifestations in Berardinelli-Seip congenital lipodystrophy type 2 (BSCL2) individuals, including lipodystrophy, hepatosteatosis, muscular hypertrophy, and insulin resistance. Metabolic defects in Bscl2 mice with regard to glucose and lipid metabolism in skeletal muscle have never been investigated. Here, we identified Bscl2 mice displayed reduced intramyocellular triglyceride (IMTG) content but increased glycogen storage predominantly in oxidative type I soleus muscle (SM).

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Background: Obesity and its associated morbidities represent the major and most rapidly expanding world-wide health epidemic. Recent genome-wide association studies (GWAS) reveal that single nucleotide polymorphism (SNP) variant in the Family with Sequence Similarity 13, Member A (FAM13A) gene is strongly associated with waist-hip ratio (WHR) with adjustment for body mass index (BMI) (WHRadjBMI). However, the function of FAM13A in adipose development and obesity remains largely uncharacterized.

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