Publications by authors named "Wenqiong Lv"
TAL1 T-cell acute lymphoblastic leukemia (T-ALL) is a distinct subtype of leukemia with poor outcomes. Through the cooperation of co-activators, including RUNX1, GATA3, and MYB, the TAL1 oncoprotein extends the immature thymocytes with autonomy and plays an important role in the development of T-ALL. However, this process is not yet well understood.
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- - Mucolipidosis type II (MLII), also known as I-cell disease, is a rare and severe lysosomal storage disease characterized by various serious health issues starting from early infancy, with a median diagnosis at 0.7 years and a median survival of about 5 years.
- - Researchers identified novel mutations in a specific gene associated with MLII and reported the first use of hematopoietic stem cell transplantation (HSCT) in a patient, which showed promising improvements in motor skills and muscle tension after the procedure.
- - Despite the positive initial results from HSCT, more long-term studies are needed to determine its true effectiveness and impact on life quality for MLII patients, as current data is limited.
T-cell acute lymphoblastic leukemia (T-ALL) is a type of aggressive leukemia with inferior prognosis. Although activating mutations of are observed in most T-ALL cases, these mutations alone are not sufficient to drive the full development of T-ALL. β-Arrestins (ARRB) are versatile and multifunctional adapter proteins that regulate diverse cellular functions, including promoting the development of cancer.
View Article and Find Full Text PDFGlucose-6-phosphate dehydrogenase (G6PD) deficiency is one of the most common X-linked enzymopathies caused by G6PD gene variant. We aimed to provide the characteristics of G6PD deficiency and G6PD gene variant distribution in a large Chinese newborn screening population. We investigated the prevalence of G6PD in China from 2013 to 2017.
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