Publications by authors named "Wenqing Shi"

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  • Phytoplankton in lakes capture atmospheric CO2 and convert it to organic carbon (OC), but most OC is recycled back to the atmosphere as CO and methane (CH), contributing to climate change.
  • * The research identifies a 3.1-fold increase in CO-equivalent emissions over the next century, exacerbated by climate warming.
  • * While climate change boosts phytoplankton growth in many lakes, it can also negatively impact their ability to sequester CO-eq, potentially weakening this feedback loop over time.
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  • Rhubarb, including raw and processed forms, is commonly used for treating gastric ulcers, but the active ingredients, mechanisms, and safety are not well understood.
  • A study identified 183, 120, and 115 compounds in raw, steamed, and carbonized rhubarb, respectively, and found key active constituents and therapeutic targets for gastric ulcer treatment through network pharmacology and molecular docking.
  • The research revealed potential effective compounds along with their targets and signaling pathways, but also highlighted concerns about liver injury associated with some of these compounds.
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  • - A new method for synthesizing resibufogenin and bufalin was developed using only seven steps without the need for protecting groups, starting from androstenedione (AD).
  • - The synthesis involved introducing a hydroxyl group at C14 using hydroxylase P-450, which helped control the configuration at C17 during subsequent reactions.
  • - The final steps included dehydrating the intermediate and using epoxidation to produce resibufogenin, while bufalin was synthesized through a more complex anaerobic Mukaiyama hydration process.
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In marine environments, a wide variety of microbes like bacteria, and archaea influence on the corrosion of materials. Viruses are widely distributed in biofilms among these microbes and may affect the corrosion process through interactions with key corrosive prokaryotes. However, understanding of the viral communities within biofilms and their interactions with corrosive microbes remains is limited.

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Objective: This study aims to explore the causal relationship between inflammatory markers and myopia through the use of bidirectional Mendelian randomization (MR) and myopia animal models.

Methods: The authors utilized data from a comprehensive and publicly accessible genome-wide association study (GWAS) for our analysis, which includes 460 536 European ancestry control subjects and 37 362 myopia patients. Utilizing a two-sample Mendelian randomization analysis framework, 27 inflammatory markers were investigated as exposure variables with myopia serving as the outcome variable.

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To evaluate the changes of choroidal thickness (CT) and blood flow related to myopia, and its effects of vascular endothelial growth factor (VEGFA) on choroidal vessels in myopia. Subjects were included and divided into emmetropia (EM), non-high myopia (Non-HM) and high myopia (HM) groups. we measured choroidal thickness (CT), choriocapillaris vessel density (VD), and VEGFA content in tears in humans (137 subjects for CT, VD and 84 for tear) and detected the role of VEGFA in the choroid in form-deprivation myopia (FDM) in guinea pigs.

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Depression is a neurodevelopmental disorder that exhibits progressive gray matter volume (GMV) atrophy. Research indicates that brain development is influential in depression-induced GMV alterations. However, the interaction between depression and age of onset is not well understood by the underlying molecular and neuropathological mechanisms.

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The annual increase in myopia prevalence poses a significant economic and health challenge. Our study investigated the effect of calcitriol role in myopia by inducing the condition in guinea pigs through form deprivation for four weeks. Untargeted metabolomics methods were used to analyze the differences in metabolites in the vitreous body, and the expression of vitamin D receptor (VDR) in the retina was detected.

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This research was designed to estimate the contributions of phosphorus (P) in different factions from an upstream plain river network to algal growth in a downstream shallow eutrophic lake, Taihu Lake, in China. During three flow regimes, the P fractions in multiple phases (particulate, colloidal and dissolved phases) and their algal availabilities were assessed via bioassays with Dolichospermum flos-aquae as the test organism. The P partitioning patterns among multiple phases were strongly affected by the concentration of total suspended solids (TSS) that changed with the river flow regime, with stronger disturbance of sediments at lower water levels (low flow) and weaker disturbance of sediments at higher water levels (high flow) in the plain river network.

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  • The study aimed to identify key mental health challenges faced by hospital administrators working from home during the COVID-19 normalization phase.
  • Conducted via surveys with 33 administrators, the research utilized the DEMATEL method to establish relationships between various mental health factors affecting their work.
  • Findings highlight that major issues include lack of coordination, time management difficulties, and work-life imbalances, with recommendations to improve conditions around improper guidelines and job insecurity to support their mental well-being.
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Increasing storage root number is a pivotal approach to enhance both storage root (SR) yield and appearance quality of sweet potato. Here, 2-year field experiments were conducted to investigate the effect of 0 (K0), 120 (K1), 240 (K2), and 360 (K3) kg ha potassium fertilizer (KO) on lignin metabolism, root growth, storage root yield, and uniformity. The results demonstrated that potassium (K) application led to a decrease in the activities of key enzymes involved in lignin biosynthesis, including phenylalanine deaminase (PAL), 4-coumarate coenzyme A ligase (4-CL), cinnamic acid dehydrogenase (CAD), polyphenol oxidase (PPO), and peroxidase (POD).

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The nitrogen (N) removal characteristics in water columns and sediments of shallow lakes, influenced by various factors, may exhibit spatial variations in lakes with algal-macrophyte dominance. The N removal rates in water columns and sediments of Lake Taihu were investigated. Our findings indicated that the total N removal rates in Lake Taihu followed the order of algae-dominance > macrophyte-dominance > pelagic lake (without the presence of algae and macrophytes).

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  • * The study examines how particle size and hydrophobicity influence bubble-particle collision detachment by measuring detachment forces and recording behaviors using a high-speed camera, alongside analyzing data with MATLAB.
  • * Results reveal that higher particle hydrophobicity reduces detachment likelihood due to increased stability of aggregates, while finer particles exhibit different detachment behaviors compared to coarser particles, with fine particles sliding off bubbles while coarse ones exert enough gravity to compress the bubbles.
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In this study, Ni60-WCx coatings (x = 0, 2, 4, 6 %) on 316L stainless steel (316Lss) were prepared via laser cladding technology. We examined all specimens s for microstructure, phase composition, microhardness and electrochemistry using several characterization techniques. It shows that the microstructure of the Ni-based coatings can be changed with WC powder.

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The Yiqi Qubai (YQ) formula is a hospital preparation for treating vitiligo in China that has had reliable efficacy for decades. The formula consists of four herbs; however, the extraction process to produce the formula is obsolete and the active ingredients and mechanisms remain unknown. Therefore, in this paper, fingerprints were combined with the chemometrics method to screen high-quality herbs for the preparation of the YQ standard decoction (YQD).

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Nanofiltration (NF) membranes, extensively used in advanced wastewater treatment, have broad application prospects for the removal of emerging trace organic micropollutants (MPs). The treatment performance is affected by several factors, such as the properties of NF membranes, characteristics of target MPs, and operating conditions of the NF system concerning MP rejection. However, quantitative studies on different contributors in this context are limited.

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The role of extracellular matrix (ECM) remodeling in the axial elongation associated with myopia has not been fully elucidated, although it is considered a significant factor. EFEMP1, a regulator of ECM, has been associated with various pathological conditions. This study aimed to examine the involvement of EFEMP1 in scleral remodeling during form deprivation myopia.

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A Ni60+30%WC composite coating was prepared on the surface of Q235 steel by utilizing a high cooling rate, small thermal deformation of the substrate material, and the good metallurgical bonding characteristics of laser cladding technology. This paper focuses on the study of the composite coatings prepared under different process parameters in order to select the optimal process parameters and provide theoretical guidance for future practical applications. The macroscopic morphology and microstructure of t he composite coatings were investigated with the help of an optical microscope (OM) and a scanning electron microscope (SEM).

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Phytoplankton are key members of river ecosystems wherein they influence and regulate the health of the local environment. Headwater streams are subject to minimal human activity and serve as the sources of rivers, generally exhibiting minimal pollution and strong hydrodynamic forces. To date, the characteristics of phytoplankton communities in headwater streams have remained poorly understood.

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Constructed wetlands (CWs) have been widely applied in wastewater treatment; however, the degradation of organic pollutants within CWs leads to substantial emissions of greenhouse gases (GHGs), such as carbon dioxide, methane and nitrous oxide. Under the low-carbon economy, GHG emissions have emerged as a major concern, and have been intensively studied in the CW field. In this study, we conducted a bibliometric review using CiteSpace and a global-scale analysis of GHG emission levels based on 286 records and proposed potential approaches for the future control of GHG emissions in CWs.

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Background: Rheumatoid arthritis (RA) is a chronic, systemic autoimmune disorder that primarily causes symmetrical polyarthritis and bone deformity. In RA patients, sight-threatening inflammatory eye complications would be expected.

Objective: The objective of the study is to ascertain the macular retinal vessel density changes in RA patients and controls using optical coherence tomography angiography (OCTA), and to investigate the association between disease and microvascular density alterations.

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Respiratory rate and skin humidity are important physiological signals and have become an important basis for disease diagnosis, and they can be monitored by humidity sensors. However, it is difficult to employ high-quality humidity sensors on a broad scale due to their high cost and complex fabrication. Here, we propose a reliable, convenient, and efficient method to mass-produce humidity sensors.

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Meiotic crossovers ensure accurate chromosome segregation and increase genetic diversity. RAD51C and RAD51D play an early role in facilitating RAD51 during homologous recombination. However, their later function in meiosis is largely unknown in plants.

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